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Classification of Human Transcription Factors and Mouse Orthologs


TFClass is a classification of (so far: human and mouse) transcription factors based on the characteristics of their DNA-binding domains. It comprises six levels (superclasses, classes, families, subfamilies, genera and factor species), two of which are optional (subfamilies and factor species). More detailed explanations about the classification scheme and its criteria will be given here. The full classification can also be obtained here as html document and as ontology in obo-format.

When referring to this classification, please cite:
Wingender, E., Schoeps, T. and Dönitz, J.:
TFClass: An expandable hierarchical classification of human transcription factors
Nucleic Acids Res. 41, D165-D170 (2013). link

Superclass: , Class: , Family: , Subfamily: , Genus: , Factor species: 

Human transcription factors

Mouse transcription factors

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Definition: -
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Other Orhologs:


    ProteinAtlas: -
    BioGPS: -
    Uniprot: -


    Uniprot: -
    Logo plot
    Logo plot
    Binding sites
    Expression table
    The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

    The selected tree node is not linked to a gene, no expression data is available.