Transcription factor classification

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1 Basic domains
2 Zinc-coordinating DNA-binding domains
- 2.1 Nuclear receptors with C4 zinc fingers
- 2.2 Other C4 zinc finger-type factors
- 2.3 C2H2 zinc finger factors
  - 2.3.1 Three-zinc finger Krüppel-related
  - 2.3.2 Other factors with up to three adjacent zinc fingers
  - 2.3.3 More than 3 adjacent zinc fingers
  - 2.3.4 Factors with multiple dispersed zinc fingers
    - 2.3.4.1 ZNF417-like
    - 2.3.4.2 ZNF219-like
    - 2.3.4.3 SAL-like
    - 2.3.4.4 Ikaros
    - 2.3.4.5 HIV EP
    - 2.3.4.6 ZBTB1-like
    - 2.3.4.7 RLF-like
    - 2.3.4.8 MAZ-like
    - 2.3.4.9 ZNF532-like
    - 2.3.4.10 ZNF512
    - 2.3.4.11 ZNF658
    - 2.3.4.12 ZNF423-like
    - 2.3.4.13 ZNF639-like
    - 2.3.4.14 EVI1-like
    - 2.3.4.15 BCL11
    - 2.3.4.16 Insulinoma-associated proteins
    - 2.3.4.17 HIC
    - 2.3.4.18 ZNF518
    - 2.3.4.19 Basonuclin
    - 2.3.4.20 TRERF1-like
    - 2.3.4.21 HINFP-like
    - 2.3.4.22 ZNF526-like
    - 2.3.4.23 ZNF319-like
    - 2.3.4.24 ZNF134-like
    - 2.3.4.25 ZNF37A-like
    - 2.3.4.0.1 CASZ1
    - 2.3.4.0.2 ZNF335
    - 2.3.4.0.4 WIZ
    - 2.3.4.0.5 ZNF469
    - 2.3.4.0.6 ZFPM1
    - 2.3.4.0.7 ZBTB4
    - 2.3.4.0.9 ZBTB39
    - 2.3.4.0.10 ZNF295
    - 2.3.4.0.12 PRDM13
    - 2.3.4.0.13 ZNF646
    - 2.3.4.0.14 ZNF579
    - 2.3.4.0.16 PRDM2
    - 2.3.4.0.17 ZNF800
    - 2.3.4.0.18 ZNF618
    - 2.3.4.0.21 ZNF451
    - 2.3.4.0.22 ZNF438
    - 2.3.4.0.24 ZNF507
    - 2.3.4.0.25 ZNF236
    - 2.3.4.0.26 ZNF770
    - 2.3.4.0.28 ZFP57
    - 2.3.4.0.30 ZNF597
    - 2.3.4.0.32 PRDM15
    - 2.3.4.0.33 ZBTB41
    - 2.3.4.0.34 PRDM10
    - 2.3.4.0.36 ZNF513
    - 2.3.4.0.37 ZNF142
    - 2.3.4.0.38 FIZ1
    - 2.3.4.0.40 ZNF784
    - 2.3.4.0.41 ZNF697
    - 2.3.4.0.42 ZKSCAN5
    - 2.3.4.0.44 ZNF775
    - 2.3.4.0.45 ZNF467
    - 2.3.4.0.46 ZNF787
    - 2.3.4.0.48 ZNF48
    - 2.3.4.0.49 ZNF629
    - 2.3.4.0.50 ZNF668
    - 2.3.4.0.51 ZNF101
    - 2.3.4.0.52 ZNF251
    - 2.3.4.0.53 ZNF445
    - 2.3.4.0.56 ZSCAN20
    - 2.3.4.0.57 ZNF674
    - 2.3.4.0.60 ZNF788
    - 2.3.4.0.63 ZNF778
    - 2.3.4.0.68 ZNF519
    - 2.3.4.0.69 ZNF304
    - 2.3.4.0.70 ZNF132
    - 2.3.4.0.72 ZBTB17
    - 2.3.4.0.73 ZNF407
    - 2.3.4.0.74 E4F1
    - 2.3.4.0 unclassified
    - 2.3.4.0.3 PRDM8
    - 2.3.4.0.8 ZBTB38
    - 2.3.4.0.15 RREB1
    - 2.3.4.0.19 ZNF277
    - 2.3.4.0.23 PEG3
    - 2.3.4.0.27 REST
    - 2.3.4.0.31 PRDM4
    - 2.3.4.0.35 ZNF341
    - 2.3.4.0.39 ZNF628
    - 2.3.4.0.43 ZNF316
    - 2.3.4.0.59 ZNF195
    - 2.3.4.0.67 ZNF606
    - 2.3.4.0.71 PRDM9
    - 2.3.4.0.75 ZNF462
    - 2.3.4.0.76 ZNF644
  - 2.3.5 BED zinc finger factors
- 2.5 DM-type intertwined zinc finger factors
- 2.6 CXXC zinc finger factors
- 2.7 C2HC
- 2.8 C3H zinc finger factors
- 2.9 C2CH THAP-type zinc finger factors
3 Helix-turn-helix domains
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Subfamily: 41 Genera within this Subfamily: 3

	DNA binding domain	Whole protein
FASTA		FASTA file
Phylogenetic tree Mammalia These trees (or cladograms, since distances were ignored) were generated with a local installation of PhyML 3.0 (Guindon et al., Systematic Biology, 59(3):307-21, 2010.), by webPRANK at EBI (http://www.ebi.ac.uk/goldman-srv/webprank/), or by the web version of PhyML 3.0 (http://phylogeny.lirmm.fr). The resulting trees were visualized with iTOL v3 (http://itol.embl.de/).		Phylogeny.fr and iTOL

Select species

Selected the species for which a species report should be shown.

Ailuropoda melanoleuca, giant panda
Bos taurus, cattle
Callithrix jacchus, white-tufted-ear marmoset
Canis lupus familiaris, dog
Cavia porcellus, domestic guinea pig
Choloepus hoffmanni, Hoffmann's two-fingered sloth
Dasypus novemcinctus, nine-banded armadillo
Dipodomys ordii, Ord's kangaroo rat
Echinops telfairi, small Madagascar hedgehog
Equus caballus, horse
Erinaceus europaeus, western European hedgehog
Felis catus, domestic cat
Gorilla gorilla gorilla, western lowland gorilla
Homo sapiens, human
Ictidomys tridecemlineatus, thirteen-lined ground squirrel
Loxodonta africana, African savanna elephant
Macaca mulatta, Rhesus monkey
Macropus eugenii, tammar wallaby
Microcebus murinus, gray mouse lemur
Monodelphis domestica, gray short-tailed opossum
Mus musculus, house mouse
Mustela putorius furo, domestic ferret
Myotis lucifugus, little brown bat
Nomascus leucogenys, northern white-cheeked gibbon
Ochotona princeps, American pika
Ornithorhynchus anatinus, platypus
Oryctolagus cuniculus, rabbit
Otolemur garnettii, small-eared galago
Ovis aries, sheep
Pan troglodytes, chimpanzee
Pongo abelii, Sumatran orangutan
Procavia capensis, Cape rock hyrax
Pteropus vampyrus, large flying fox
Rattus norvegicus, Norway rat
Sarcophilus harrisii, Tasmanian devil
Sorex araneus, European shrew
Sus scrofa, pig
Tarsius syrichta, Philippine tarsier
Tupaia belangeri, northern tree shrew
Tursiops truncatus, bottlenose dolphin
Vicugna pacos, alpaca

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

The selected tree node is not linked to a gene, no expression data is available.

Classification of Transcription Factors in Mammalia

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Classification of Transcription Factors in Mammalia

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