Classification of Transcription Factors in Mammalia

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1 Basic domains
2 Zinc-coordinating DNA-binding domains
3 Helix-turn-helix domains
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
- 6.1 Rel homology region (RHR) factors
  - 6.1.1 NFkappaB-related
  - 6.1.2 Ankyrin-only
  - 6.1.3 NFAT-related
  - 6.1.4 CSL-related
  - 6.1.5 EBF-related
    - 6.1.5.0.1 EBF1
    - 6.1.5.0.2 EBF2
    - 6.1.5.0.3 EBF3
    - 6.1.5.0.4 EBF4
- 6.2 STAT domain factors
- 6.3 p53 domain factors
- 6.4 Runt domain factors
- 6.5 T-Box factors
- 6.6 NDT80 domain factors
- 6.7 Grainyhead
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 23

Species specific reports

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Ailuropoda melanoleuca

Synonyms: giant panda

Outlinks

Ensembl gene: ENSAMEG00000000326

Bos taurus

Synonyms: cattle, domestic cow

Outlinks

Ensembl gene: ENSBTAG00000040390

Callithrix jacchus

Synonyms: white-tufted-ear marmoset, white ear-tufted marmoset

Outlinks

Ensembl gene: ENSCJAG00000019921

Canis lupus familiaris

Synonyms: dog, dogs

Outlinks

Ensembl: ENSCAFG00000008918

Cavia porcellus

Synonyms: domestic guinea pig, guinea pig

Outlinks

Ensembl gene: ENSCPOG00000001463

Dasypus novemcinctus

Synonyms: nine-banded armadillo

Outlinks

Ensembl gene: ENSDNOG00000040488

Equus caballus

Synonyms: horse, equine

Outlinks

Ensembl gene: ENSECAG00000014179

Felis catus

Synonyms: domestic cat, cats

Outlinks

Ensembl gene: ENSFCAG00000003607

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000221818
Ensembl gene: ENSG00000221818
ProteinAtlas: ENSG00000221818 ( with antibody)
TRANSFAC: T18850
UniProt: Q9HAK2

Protein expression pattern:Show tableIsoforms and DNA binding domain

Ictidomys tridecemlineatus

Synonyms: thirteen-lined ground squirrel

Outlinks

Ensembl: ENSSTOG00000026314

Microcebus murinus

Synonyms: gray mouse lemur, grey mouse lemur

Outlinks

Ensembl gene: ENSMICG00000015774
UniProt: NA

Monodelphis domestica

Synonyms: gray short-tailed opossum

Outlinks

Ensembl gene: ENSMODG00000016702
UniProt: NA

Mus musculus

Synonyms: house mouse, mouse

Outlinks

Ensembl gene: ENSMUSG00000022053
TRANSFAC: T05006
UniProt: O08792

Isoforms and DNA binding domain

Myotis lucifugus

Synonyms: little brown bat

Outlinks

Ensembl gene: ENSMLUG00000011509
UniProt: NA

Nomascus leucogenys

Synonyms: northern white-cheeked gibbon, White-cheeked Gibbon

Outlinks

Ensembl: ENSMPUG00000003195
Ensembl gene: ENSPPYG00000018454
Ensembl gene: ENSNLEG00000016189
Ensembl gene: ENSGGOG00000001585
Ensembl gene: ENSPTRG00000003058
UniProt: NA
UniProt: H2Q2S3

Ornithorhynchus anatinus

Synonyms: platypus, duckbill platypus

Outlinks

Ensembl gene: ENSOANG00000004212
UniProt: NA

Oryctolagus cuniculus

Synonyms: rabbit, rabbits

Outlinks

Ensembl gene: ENSOCUG00000011972

Otolemur garnettii

Synonyms: small-eared galago

Outlinks

Ensembl gene: ENSOGAG00000010783

Ovis aries

Synonyms: sheep, wild sheep

Outlinks

Ensembl gene: ENSOARG00000009825
Ensembl gene: ENSLAFG00000022465
UniProt: NA

Rattus norvegicus

Synonyms: Norway rat, rats

Outlinks

Ensembl gene: ENSRNOG00000011548
UniProt: D3ZT68

Isoforms and DNA binding domain

Sarcophilus harrisii

Synonyms: Tasmanian devil

Outlinks

Ensembl: ENSSHAG00000011963

Sorex araneus

Synonyms: European shrew, Eurasian shrew

Outlinks

Ensembl gene: ENSSARG00000012320
UniProt: NA

Sus scrofa

Synonyms: pig, wild boar

Outlinks

Ensembl gene: ENSSSCG00000009655

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

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Tissue	Cell type	Expression level	Type	Reliability
adrenal gland	glandular tissue	Negative	Staining	Uncertain
appendix	glandular tissue	Weak	Staining	Uncertain
appendix	lymphoid tissue	Negative	Staining	Uncertain
bone barrow	hematopoetic stem cell	Strong	Staining	Uncertain
breast	glandular tissue	Weak	Staining	Uncertain
bronchi	ciliated call with propulsive function of respiratory tract	Negative	Staining	Uncertain
cerebellum	granule cell	Negative	Staining	Uncertain
cerebellum		Moderate	Staining	Uncertain
cerebellum	purkinje cell	Negative	Staining	Uncertain
cerebral cortex	glial cell of central nervous system	Negative	Staining	Uncertain
cerebral cortex	neuron	Negative	Staining	Uncertain
cervix of uterus	glandular tissue	Negative	Staining	Uncertain
cervix of uterus	squamous epithelial cell	Negative	Staining	Uncertain
colon	glandular tissue	Moderate	Staining	Uncertain
duodenum	glandular tissue	Weak	Staining	Uncertain

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