Status

Please wait ...

Classification of Transcription Factors in Mammalia

About TFClass

Search in TFClass:

Go to the search of TRANSFAC

Superclass:

, Class:

,
Family:

, Subfamily:

, Genus:

,

1 Basic domains
- 1.1 Basic leucine zipper factors (bZIP)
- 1.2 Basic helix-loop-helix factors (bHLH)
  - 1.2.1 E2A
  - 1.2.2 MyoD-ASC-related
  - 1.2.3 Tal-related
    - 1.2.3.1 TAL-HEN
    - 1.2.3.2 TWIST
    - 1.2.3.3 MESP
    - 1.2.3.4 Neurogenin-ATO
      - 1.2.3.4.1 NEUROD1
      - 1.2.3.4.2 NEUROD2
      - 1.2.3.4.3 NEUROD4
      - 1.2.3.4.4 NEUROD6
      - 1.2.3.4.5 NGN1/NEUROG1
      - 1.2.3.4.6 NGN2/NEUROG2
      - 1.2.3.4.7 NGN3/NEUROG3
      - 1.2.3.4.8 ATOH1
      - 1.2.3.4.9 ATOH7
      - 1.2.3.4.10 ATOH8
      - 1.2.3.4.11 BHLHE22
      - 1.2.3.4.12 BHLHE23
      - 1.2.3.4.13 OLIG1
      - 1.2.3.4.14 OLIG2
      - 1.2.3.4.15 OLIG3
      - 1.2.3.4.16 BHLHA15
      - 1.2.3.4.17 FERD3L
    - 1.2.3.5 BHLHA9
  - 1.2.4 Hairy-related
  - 1.2.5 PAS
  - 1.2.6 bHLH-ZIP
  - 1.2.8 HLH only
- 1.3 Basic helix-span-helix factors (bHSH)
2 Zinc-coordinating DNA-binding domains
3 Helix-turn-helix domains
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 21 LOGO plot of the DNA binding sequence

Species specific reports

Jump to human, mouse or rat
Hint: You can rearrange the panels by drag-and-drop. The new arrangement will persist during your session.

Bos taurus

Synonyms: cattle, domestic cow

Outlinks

Ensembl gene: ENSBTAG00000037547

Canis lupus familiaris

Synonyms: dog, dogs

Outlinks

Ensembl: ENSCAFG00000031953

Cavia porcellus

Synonyms: domestic guinea pig, guinea pig

Outlinks

Ensembl: ENSCPOG00000020839

Dasypus novemcinctus

Synonyms: nine-banded armadillo

Outlinks

Ensembl gene: ENSDNOG00000042196

Echinops telfairi

Synonyms: small Madagascar hedgehog, lesser hedgehog tenrec

Outlinks

Ensembl gene: ENSETEG00000011024
UniProt: NA

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000184221
Ensembl gene: ENSG00000184221
ProteinAtlas: ENSG00000184221 ( with antibody)
TRANSFAC: T05855
UniProt: Q8TAK6

Protein expression pattern:Show tableIsoforms and DNA binding domain

Ictidomys tridecemlineatus

Synonyms: thirteen-lined ground squirrel

Outlinks

Ensembl gene: ENSSTOG00000027713
UniProt: NA

Loxodonta africana

Synonyms: African savanna elephant, African savannah elephant

Outlinks

Ensembl gene: ENSLAFG00000007964
UniProt: NA

Macaca mulatta

Synonyms: Rhesus monkey, rhesus monkeys

Outlinks

Ensembl gene: ENSMMUG00000001558

Monodelphis domestica

Synonyms: gray short-tailed opossum

Outlinks

Ensembl gene: ENSMODG00000021070
UniProt: NA

Mus musculus

Synonyms: house mouse, mouse

Outlinks

Ensembl gene: ENSMUSG00000046160
TRANSFAC: T05853
UniProt: Q9JKN5

Isoforms and DNA binding domain

Ochotona princeps

Synonyms: American pika, southern American pika

Outlinks

Ensembl gene: ENSOPRG00000007722
UniProt: NA

Ornithorhynchus anatinus

Synonyms: platypus, duckbill platypus

Outlinks

Ensembl gene: ENSOANG00000002423
UniProt: NA

Oryctolagus cuniculus

Synonyms: rabbit, rabbits

Outlinks

Ensembl gene: ENSOCUG00000027389

Otolemur garnettii

Synonyms: small-eared galago

Outlinks

Ensembl gene: ENSOGAG00000033584
UniProt: B5SNH7

Isoforms and DNA binding domain

Pan troglodytes

Synonyms: chimpanzee

Outlinks

Ensembl gene: ENSPTRG00000031440

Pteropus vampyrus

Synonyms: large flying fox

Outlinks

Ensembl gene: ENSPVAG00000001702
UniProt: NA

Rattus norvegicus

Synonyms: Norway rat, rats

Outlinks

Ensembl gene: ENSRNOG00000028648

Sarcophilus harrisii

Synonyms: Tasmanian devil

Outlinks

Ensembl gene: ENSSHAG00000004906
UniProt: NA

Sus scrofa

Synonyms: pig, wild boar

Outlinks

Ensembl gene: ENSSSCG00000012040

Vicugna pacos

Synonyms: alpaca

Outlinks

Ensembl gene: ENSVPAG00000005098
UniProt: NA

Select species

Selected the species for which a species report should be shown.

Ailuropoda melanoleuca, giant panda
Bos taurus, cattle
Callithrix jacchus, white-tufted-ear marmoset
Canis lupus familiaris, dog
Cavia porcellus, domestic guinea pig
Choloepus hoffmanni, Hoffmann's two-fingered sloth
Dasypus novemcinctus, nine-banded armadillo
Dipodomys ordii, Ord's kangaroo rat
Echinops telfairi, small Madagascar hedgehog
Equus caballus, horse
Erinaceus europaeus, western European hedgehog
Felis catus, domestic cat
Gorilla gorilla gorilla, western lowland gorilla
Homo sapiens, human
Ictidomys tridecemlineatus, thirteen-lined ground squirrel
Loxodonta africana, African savanna elephant
Macaca mulatta, Rhesus monkey
Macropus eugenii, tammar wallaby
Microcebus murinus, gray mouse lemur
Monodelphis domestica, gray short-tailed opossum
Mus musculus, house mouse
Mustela putorius furo, domestic ferret
Myotis lucifugus, little brown bat
Nomascus leucogenys, northern white-cheeked gibbon
Ochotona princeps, American pika
Ornithorhynchus anatinus, platypus
Oryctolagus cuniculus, rabbit
Otolemur garnettii, small-eared galago
Ovis aries, sheep
Pan troglodytes, chimpanzee
Pongo abelii, Sumatran orangutan
Procavia capensis, Cape rock hyrax
Pteropus vampyrus, large flying fox
Rattus norvegicus, Norway rat
Sarcophilus harrisii, Tasmanian devil
Sorex araneus, European shrew
Sus scrofa, pig
Tarsius syrichta, Philippine tarsier
Tupaia belangeri, northern tree shrew
Tursiops truncatus, bottlenose dolphin
Vicugna pacos, alpaca

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

pp12345pp

Tissue	Cell type	Expression level	Type	Reliability
adrenal gland	glandular tissue	Moderate	Staining	Uncertain
appendix	glandular tissue	Moderate	Staining	Uncertain
appendix	lymphoid tissue	Moderate	Staining	Uncertain
bone barrow	hematopoetic stem cell	Moderate	Staining	Uncertain
breast	glandular tissue	Moderate	Staining	Uncertain
bronchi	ciliated call with propulsive function of respiratory tract	Moderate	Staining	Uncertain
cerebellum	granule cell	Moderate	Staining	Uncertain
cerebellum		Moderate	Staining	Uncertain
cerebellum	purkinje cell	Moderate	Staining	Uncertain
cerebral cortex	glial cell of central nervous system	Moderate	Staining	Uncertain
cerebral cortex	neuron	Moderate	Staining	Uncertain
cervix of uterus	glandular tissue	Moderate	Staining	Uncertain
cervix of uterus	squamous epithelial cell	Moderate	Staining	Uncertain
colon	glandular tissue	Moderate	Staining	Uncertain
duodenum	glandular tissue	Moderate	Staining	Uncertain

pp12345pp