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Classification of Transcription Factors in Mammalia

About TFClass

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Family:

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, Genus:

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1 Basic domains
2 Zinc-coordinating DNA-binding domains
3 Helix-turn-helix domains
- 3.1 Homeo domain factors
  - 3.1.1 HOX
  - 3.1.2 NK
  - 3.1.3 Paired-related HD
    - 3.1.3.1 ALX
    - 3.1.3.2 ARGFX
    - 3.1.3.3 ARX
    - 3.1.3.4 DMBX
    - 3.1.3.5 DPRX
    - 3.1.3.6 DRGX
    - 3.1.3.7 DUX
    - 3.1.3.8 ESX
    - 3.1.3.9 GSC
    - 3.1.3.10 HESX
    - 3.1.3.11 HOPX
    - 3.1.3.12 ISX
    - 3.1.3.13 LEUTX
    - 3.1.3.14 MIX
    - 3.1.3.15 NOBOX
    - 3.1.3.16 OTP
    - 3.1.3.17 OTX
    - 3.1.3.18 PHOX
    - 3.1.3.19 PITX
    - 3.1.3.20 PROP
    - 3.1.3.21 PRRX
    - 3.1.3.22 RAX
    - 3.1.3.23 RHOX
      - 3.1.3.23.1 RHOXF1
      - 3.1.3.23.2 RHOXF2
    - 3.1.3.24 SEBOX
    - 3.1.3.25 SHOX
    - 3.1.3.26 TPRX
    - 3.1.3.27 UNCX
    - 3.1.3.28 VSX
  - 3.1.4 TALE-type HD
  - 3.1.5 HD-LIM
  - 3.1.6 HD-SINE
  - 3.1.7 HD-PROS
  - 3.1.8 HD-ZF
  - 3.1.9 HD-CUT
  - 3.1.10 POU
  - 3.1.11 PHTF
- 3.2 Paired box factors
- 3.3 Fork head / winged helix factors
- 3.4 Heat shock factors
- 3.5 Tryptophan cluster factors
- 3.6 TEA domain factors
- 3.7 ARID
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 22 LOGO plot of the DNA binding sequence

Species specific reports

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Ailuropoda melanoleuca

Synonyms: giant panda

Outlinks

Ensembl gene: ENSAMEG00000000182

Callithrix jacchus

Synonyms: white-tufted-ear marmoset, white ear-tufted marmoset

Outlinks

Ensembl gene: ENSCJAG00000004938

Canis lupus familiaris

Synonyms: dog, dogs

Outlinks

Ensembl: ENSCAFG00000030907
Ensembl: ENSCAFG00000018454

Dasypus novemcinctus

Synonyms: nine-banded armadillo

Outlinks

Ensembl gene: ENSDNOG00000037814

Dipodomys ordii

Synonyms: Ord's kangaroo rat

Outlinks

Ensembl: ENSDORG00000003153

Gorilla gorilla gorilla

Synonyms: western lowland gorilla, lowland gorilla

Outlinks

Ensembl gene: ENSGGOG00000016112

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000101883
Ensembl gene: ENSG00000101883
ProteinAtlas: ENSG00000101883 ( with antibody)
TRANSFAC: T19783
UniProt: Q8NHV9

Isoforms and DNA binding domain

Ictidomys tridecemlineatus

Synonyms: thirteen-lined ground squirrel

Outlinks

Ensembl: ENSSTOG00000005297
Ensembl: ENSSTOG00000001145

Macaca mulatta

Synonyms: Rhesus monkey, rhesus monkeys

Outlinks

Ensembl: ENSMMUG00000013600

Microcebus murinus

Synonyms: gray mouse lemur, grey mouse lemur

Outlinks

Ensembl: ENSMICG00000002411

Mus musculus

Synonyms: house mouse, mouse

Outlinks

Ensembl gene: ENSMUSG00000097126
Ensembl gene: ENSMUSG00000071766
Ensembl gene: ENSMUSG00000006200
Ensembl gene: ENSMUSG00000064137
Ensembl gene: ENSMUSG00000068048
Ensembl gene: ENSMUSG00000097436
UniProt: Q4TU81
UniProt: Q6VSS7
UniProt: O70238
UniProt: Q9EQM5

Isoforms and DNA binding domain

Myotis lucifugus

Synonyms: little brown bat

Outlinks

Ensembl gene: ENSMLUG00000007665
UniProt: NA

Oryctolagus cuniculus

Synonyms: rabbit, rabbits

Outlinks

Ensembl gene: ENSOCUG00000024319

Otolemur garnettii

Synonyms: small-eared galago

Outlinks

Ensembl gene: ENSOGAG00000030871
Ensembl gene: ENSOGAG00000030942

Ovis aries

Synonyms: sheep, wild sheep

Outlinks

Ensembl gene: ENSOARG00000011937

Pongo abelii

Synonyms: Sumatran orangutan, orang utan

Outlinks

Ensembl gene: ENSPPYG00000020680

Pteropus vampyrus

Synonyms: large flying fox

Outlinks

Ensembl gene: ENSPVAG00000009422
UniProt: NA

Rattus norvegicus

Synonyms: Norway rat, rats

Outlinks

Ensembl: ENSRNOG00000007526
Ensembl gene: ENSRNOG00000040033
Ensembl gene: ENSRNOG00000050457
UniProt: Q4TU71

Isoforms and DNA binding domain

Sus scrofa

Synonyms: pig, wild boar

Outlinks

Ensembl: ENSSSCG00000012611

Tarsius syrichta

Synonyms: Philippine tarsier

Outlinks

Ensembl: ENSTSYG00000000237

Tupaia belangeri

Synonyms: northern tree shrew, common tree shrew

Outlinks

Ensembl gene: ENSTBEG00000007209
Ensembl gene: ENSTBEG00000002729
UniProt: NA

Tursiops truncatus

Synonyms: bottlenose dolphin, bottle-nosed dolphin

Outlinks

Ensembl gene: ENSTTRG00000006609
Ensembl gene: ENSTTRG00000011470
Ensembl gene: ENSTTRG00000011466
UniProt: NA

Select species

Selected the species for which a species report should be shown.

Ailuropoda melanoleuca, giant panda
Bos taurus, cattle
Callithrix jacchus, white-tufted-ear marmoset
Canis lupus familiaris, dog
Cavia porcellus, domestic guinea pig
Choloepus hoffmanni, Hoffmann's two-fingered sloth
Dasypus novemcinctus, nine-banded armadillo
Dipodomys ordii, Ord's kangaroo rat
Echinops telfairi, small Madagascar hedgehog
Equus caballus, horse
Erinaceus europaeus, western European hedgehog
Felis catus, domestic cat
Gorilla gorilla gorilla, western lowland gorilla
Homo sapiens, human
Ictidomys tridecemlineatus, thirteen-lined ground squirrel
Loxodonta africana, African savanna elephant
Macaca mulatta, Rhesus monkey
Macropus eugenii, tammar wallaby
Microcebus murinus, gray mouse lemur
Monodelphis domestica, gray short-tailed opossum
Mus musculus, house mouse
Mustela putorius furo, domestic ferret
Myotis lucifugus, little brown bat
Nomascus leucogenys, northern white-cheeked gibbon
Ochotona princeps, American pika
Ornithorhynchus anatinus, platypus
Oryctolagus cuniculus, rabbit
Otolemur garnettii, small-eared galago
Ovis aries, sheep
Pan troglodytes, chimpanzee
Pongo abelii, Sumatran orangutan
Procavia capensis, Cape rock hyrax
Pteropus vampyrus, large flying fox
Rattus norvegicus, Norway rat
Sarcophilus harrisii, Tasmanian devil
Sorex araneus, European shrew
Sus scrofa, pig
Tarsius syrichta, Philippine tarsier
Tupaia belangeri, northern tree shrew
Tursiops truncatus, bottlenose dolphin
Vicugna pacos, alpaca

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology