Transcription factor classification

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1 Basic domains
2 Zinc-coordinating DNA-binding domains
- 2.1 Nuclear receptors with C4 zinc fingers
- 2.2 Other C4 zinc finger-type factors
- 2.3 C2H2 zinc finger factors
  - 2.3.1 Three-zinc finger Krüppel-related
  - 2.3.2 Other factors with up to three adjacent zinc fingers
    - 2.3.2.1 BTB-POZ
    - 2.3.2.2 KRAB
    - 2.3.2.3 SCAN
    - 2.3.2.4 Other
      - 2.3.2.4.1 ZNF414
      - 2.3.2.4.2 ZNF511
      - 2.3.2.4.3 ZNF580
      - 2.3.2.4.5 ZNF740
      - 2.3.2.4.6 ZFPM2
      - 2.3.2.4.7 OSR1
      - 2.3.2.4.8 OVOL3
      - 2.3.2.4.9 AEBP2
  - 2.3.3 More than 3 adjacent zinc fingers
  - 2.3.4 Factors with multiple dispersed zinc fingers
  - 2.3.5 BED zinc finger factors
- 2.5 DM-type intertwined zinc finger factors
- 2.6 CXXC zinc finger factors
- 2.7 C2HC
- 2.8 C3H zinc finger factors
- 2.9 C2CH THAP-type zinc finger factors
3 Helix-turn-helix domains
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 36 LOGO plot of the DNA binding sequence

Species specific reports

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Ailuropoda melanoleuca

Synonyms: giant panda

Outlinks

Ensembl gene: ENSAMEG00000012221

Bos taurus

Synonyms: cattle, domestic cow

Outlinks

Ensembl gene: ENSBTAG00000046481
Ensembl gene: ENSBTAG00000016502

Callithrix jacchus

Synonyms: white-tufted-ear marmoset, white ear-tufted marmoset

Outlinks

Ensembl gene: ENSCJAG00000018381
UniProt: F7ABG6

Isoforms and DNA binding domain

Canis lupus familiaris

Synonyms: dog, dogs

Outlinks

Ensembl: ENSCAFG00000007070

Cavia porcellus

Synonyms: domestic guinea pig, guinea pig

Outlinks

Ensembl: ENSCPOG00000014815

Dasypus novemcinctus

Synonyms: nine-banded armadillo

Outlinks

Ensembl gene: ENSDNOG00000033888

Dipodomys ordii

Synonyms: Ord's kangaroo rat

Outlinks

Ensembl: ENSDORG00000002972

Echinops telfairi

Synonyms: small Madagascar hedgehog, lesser hedgehog tenrec

Outlinks

Ensembl gene: ENSETEG00000006127
UniProt: NA

Equus caballus

Synonyms: horse, equine

Outlinks

Ensembl gene: ENSECAG00000013071

Erinaceus europaeus

Synonyms: western European hedgehog, common hedgehog

Outlinks

Ensembl gene: ENSEEUG00000005151
UniProt: NA

Felis catus

Synonyms: domestic cat, cats

Outlinks

Ensembl gene: ENSFCAG00000005868

Gorilla gorilla gorilla

Synonyms: western lowland gorilla, lowland gorilla

Outlinks

Ensembl gene: ENSGGOG00000006790

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000139651
Ensembl gene: ENSG00000139651
ProteinAtlas: ENSG00000139651 ( with antibody)
TRANSFAC: T23591
UniProt: Q8NDX6

Protein expression pattern:Show tableIsoforms and DNA binding domain

Ictidomys tridecemlineatus

Synonyms: thirteen-lined ground squirrel

Outlinks

Ensembl gene: ENSSTOG00000011188
UniProt: NA

Loxodonta africana

Synonyms: African savanna elephant, African savannah elephant

Outlinks

Ensembl gene: ENSLAFG00000009191
UniProt: NA

Macaca mulatta

Synonyms: Rhesus monkey, rhesus monkeys

Outlinks

Ensembl gene: ENSMMUG00000005246
UniProt: H9ESF7

Isoforms and DNA binding domain

Macropus eugenii

Synonyms: tammar wallaby

Outlinks

Ensembl: ENSMEUG00000003745

Microcebus murinus

Synonyms: gray mouse lemur, grey mouse lemur

Outlinks

Ensembl gene: ENSMICG00000014191
UniProt: NA

Mus musculus

Synonyms: house mouse, mouse

Outlinks

Ensembl gene: ENSMUSG00000046897
TRANSFAC: T16895
UniProt: Q6NZQ6

Isoforms and DNA binding domain

Mustela putorius furo

Synonyms: domestic ferret, ferret

Outlinks

Ensembl: ENSMPUG00000006131

Myotis lucifugus

Synonyms: little brown bat

Outlinks

Ensembl gene: ENSMLUG00000017275
UniProt: NA

Nomascus leucogenys

Synonyms: northern white-cheeked gibbon, White-cheeked Gibbon

Outlinks

Ensembl gene: ENSNLEG00000017717
UniProt: NA

Ochotona princeps

Synonyms: American pika, southern American pika

Outlinks

Ensembl gene: ENSOPRG00000015554
UniProt: NA

Oryctolagus cuniculus

Synonyms: rabbit, rabbits

Outlinks

Ensembl gene: ENSOCUG00000001422

Otolemur garnettii

Synonyms: small-eared galago

Outlinks

Ensembl gene: ENSOGAG00000025330

Ovis aries

Synonyms: sheep, wild sheep

Outlinks

Ensembl gene: ENSOARG00000016661

Pan troglodytes

Synonyms: chimpanzee

Outlinks

Ensembl gene: ENSPTRG00000005005
UniProt: H2Q614

Isoforms and DNA binding domain

Pongo abelii

Synonyms: Sumatran orangutan, orang utan

Outlinks

Ensembl gene: ENSPPYG00000004570

Rattus norvegicus

Synonyms: Norway rat, rats

Outlinks

Ensembl gene: ENSRNOG00000012192

Sarcophilus harrisii

Synonyms: Tasmanian devil

Outlinks

Ensembl gene: ENSSHAG00000000623
UniProt: NA

Sorex araneus

Synonyms: European shrew, Eurasian shrew

Outlinks

Ensembl gene: ENSSARG00000012946
UniProt: NA

Sus scrofa

Synonyms: pig, wild boar

Outlinks

Ensembl: ENSSSCG00000000256

Tarsius syrichta

Synonyms: Philippine tarsier

Outlinks

Ensembl: ENSTSYG00000010942

Tupaia belangeri

Synonyms: northern tree shrew, common tree shrew

Outlinks

Ensembl gene: ENSTBEG00000015437
UniProt: NA

Tursiops truncatus

Synonyms: bottlenose dolphin, bottle-nosed dolphin

Outlinks

Ensembl gene: ENSTTRG00000002776
UniProt: NA

Vicugna pacos

Synonyms: alpaca

Outlinks

Ensembl gene: ENSVPAG00000000947
UniProt: NA

Select species

Selected the species for which a species report should be shown.

Ailuropoda melanoleuca, giant panda
Bos taurus, cattle
Callithrix jacchus, white-tufted-ear marmoset
Canis lupus familiaris, dog
Cavia porcellus, domestic guinea pig
Choloepus hoffmanni, Hoffmann's two-fingered sloth
Dasypus novemcinctus, nine-banded armadillo
Dipodomys ordii, Ord's kangaroo rat
Echinops telfairi, small Madagascar hedgehog
Equus caballus, horse
Erinaceus europaeus, western European hedgehog
Felis catus, domestic cat
Gorilla gorilla gorilla, western lowland gorilla
Homo sapiens, human
Ictidomys tridecemlineatus, thirteen-lined ground squirrel
Loxodonta africana, African savanna elephant
Macaca mulatta, Rhesus monkey
Macropus eugenii, tammar wallaby
Microcebus murinus, gray mouse lemur
Monodelphis domestica, gray short-tailed opossum
Mus musculus, house mouse
Mustela putorius furo, domestic ferret
Myotis lucifugus, little brown bat
Nomascus leucogenys, northern white-cheeked gibbon
Ochotona princeps, American pika
Ornithorhynchus anatinus, platypus
Oryctolagus cuniculus, rabbit
Otolemur garnettii, small-eared galago
Ovis aries, sheep
Pan troglodytes, chimpanzee
Pongo abelii, Sumatran orangutan
Procavia capensis, Cape rock hyrax
Pteropus vampyrus, large flying fox
Rattus norvegicus, Norway rat
Sarcophilus harrisii, Tasmanian devil
Sorex araneus, European shrew
Sus scrofa, pig
Tarsius syrichta, Philippine tarsier
Tupaia belangeri, northern tree shrew
Tursiops truncatus, bottlenose dolphin
Vicugna pacos, alpaca

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

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Tissue	Cell type	Expression level	Type	Reliability
adrenal gland	glandular tissue	Moderate	Staining	Uncertain
appendix	glandular tissue	Moderate	Staining	Uncertain
appendix	lymphoid tissue	Moderate	Staining	Uncertain
bone barrow	hematopoetic stem cell	Moderate	Staining	Uncertain
breast	glandular tissue	Moderate	Staining	Uncertain
bronchi	ciliated call with propulsive function of respiratory tract	Strong	Staining	Uncertain
cerebellum	granule cell	Moderate	Staining	Uncertain
cerebellum		Moderate	Staining	Uncertain
cerebellum	purkinje cell	Negative	Staining	Uncertain
cerebral cortex	glial cell of central nervous system	Moderate	Staining	Uncertain
cerebral cortex	neuron	Negative	Staining	Uncertain
cervix of uterus	glandular tissue	Moderate	Staining	Uncertain
cervix of uterus	squamous epithelial cell	Moderate	Staining	Uncertain
colon	glandular tissue	Moderate	Staining	Uncertain
duodenum	glandular tissue	Moderate	Staining	Uncertain

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Classification of Transcription Factors in Mammalia

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Species specific reports

Classification of Transcription Factors in Mammalia

About TFClass

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Species specific reports

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