Transcription factor classification

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1 Basic domains
2 Zinc-coordinating DNA-binding domains
- 2.1 Nuclear receptors with C4 zinc fingers
- 2.2 Other C4 zinc finger-type factors
- 2.3 C2H2 zinc finger factors
  - 2.3.1 Three-zinc finger Krüppel-related
  - 2.3.2 Other factors with up to three adjacent zinc fingers
  - 2.3.3 More than 3 adjacent zinc fingers
    - 2.3.3.1 GLI-lile
    - 2.3.3.2 Snail-like
    - 2.3.3.3 ZFP91-like
    - 2.3.3.4 ZNF280-like
    - 2.3.3.5 ZSCAN5-like
    - 2.3.3.6 ZNF75-like
    - 2.3.3.7 ZNF705
    - 2.3.3.8 ZBTB7
    - 2.3.3.9 YY1-like
    - 2.3.3.10 ZNF24-like
    - 2.3.3.11 ZBTB6-like
    - 2.3.3.12 PRDM1-like
    - 2.3.3.13 ZNF148-like
    - 2.3.3.14 ZBTB20-like
    - 2.3.3.15 ZNF524-like
    - 2.3.3.16 ZNF238-like
    - 2.3.3.17 OVOL
    - 2.3.3.18 ZNF56-like
    - 2.3.3.19 ZNF500-like
    - 2.3.3.20 FEZF
    - 2.3.3.21 GFI1
    - 2.3.3.22 BCL6
    - 2.3.3.23 ZNF212-like
    - 2.3.3.24 MTF1-like
    - 2.3.3.25 PLAG
    - 2.3.3.26 ZKSCAN3-like
    - 2.3.3.27 ZNF525-like
    - 2.3.3.28 ZNF76-like
    - 2.3.3.29 ZNF652-like
    - 2.3.3.30 ZNF350-like
    - 2.3.3.31 ZNF642-like
    - 2.3.3.32 ZNF679-like
    - 2.3.3.33 ZNF763-like
    - 2.3.3.34 ZNF3-like
    - 2.3.3.35 ZNF620-like
    - 2.3.3.36 ZNF324
    - 2.3.3.37 ZNF362-like
    - 2.3.3.38 ZNF282-like
    - 2.3.3.39 ZNF764-like
    - 2.3.3.40 ZNF177-like
    - 2.3.3.41 ZNF32-like
    - 2.3.3.42 ZNF773-like
    - 2.3.3.43 ZNF558-like
    - 2.3.3.44 ZNF302-like
    - 2.3.3.45 ZNF562-like
    - 2.3.3.46 ZXD
    - 2.3.3.47 ZNF222-like
    - 2.3.3.48 ZNF736-like
    - 2.3.3.49 ZNF286
    - 2.3.3.50 CTCF-like
    - 2.3.3.51 ZNF366-like
    - 2.3.3.52 ZNF322-like
    - 2.3.3.53 ZNF548-like
    - 2.3.3.54 ZNF460-like
    - 2.3.3.55 ZNF146-like
    - 2.3.3.56 ZNF214-like
    - 2.3.3.57 ZNF479-like
    - 2.3.3.58 ZNF180-like
    - 2.3.3.59 ZNF100-like
    - 2.3.3.60 ZNF98-like
    - 2.3.3.61 ZNF343-like
    - 2.3.3.62 ZFP2-like
    - 2.3.3.63 ZFP30-like
    - 2.3.3.64 ZNF354A-like
    - 2.3.3.65 ZFX-ZFY
    - 2.3.3.66 ZNF689-like
    - 2.3.3.67 ZNF283-like
    - 2.3.3.68 ZNF81-like
    - 2.3.3.69 ZNF25-like
    - 2.3.3.70 ZNF26-like
    - 2.3.3.71 ZNF300-like
    - 2.3.3.72 ZNF813-like
    - 2.3.3.73 ZNF816A-like
    - 2.3.3.74 ZNF442-like
    - 2.3.3.75 ZNF432-like
    - 2.3.3.76 ZNF665-like
    - 2.3.3.77 ZNF595-like
    - 2.3.3.78 ZNF14-like
    - 2.3.3.79 ZNF841-like
    - 2.3.3.80 ZNF99-like
    - 2.3.3.0.1 ZFP161
    - 2.3.3.0.10 ZNF781
    - 2.3.3.0.11 ZNF114
    - 2.3.3.0.12 ZNF589
    - 2.3.3.0.13 ZNF22
    - 2.3.3.0.14 ZNF713
    - 2.3.3.0.15 ZSCAN16
    - 2.3.3.0.20 ZNF18
    - 2.3.3.0.21 WT1
    - 2.3.3.0.23 PRDM6
    - 2.3.3.0.24 ZNF444
    - 2.3.3.0.25 ZNF641
    - 2.3.3.0.26 ZNF746
    - 2.3.3.0.27 ZIM2
    - 2.3.3.0.31 ZNF655
    - 2.3.3.0.32 ZNF165
    - 2.3.3.0.34 ZNF131
    - 2.3.3.0.35 PRDM14
    - 2.3.3.0.37 ZNF575
    - 2.3.3.0.38 ZBTB49
    - 2.3.3.0.39 ZNF691
    - 2.3.3.0.43 ZSCAN30
    - 2.3.3.0.45 ZNF80
    - 2.3.3.0.46 ZNF514
    - 2.3.3.0.47 ZSCAN21
    - 2.3.3.0.54 MYNN
    - 2.3.3.0.55 ZBTB24
    - 2.3.3.0.57 ZFP92
    - 2.3.3.0.58 ZNF205
    - 2.3.3.0.59 ZNF837
    - 2.3.3.0.67 ZNF584
    - 2.3.3.0.68 ZNF684
    - 2.3.3.0.69 ZNF187
    - 2.3.3.0.70 ZSCAN22
    - 2.3.3.0.71 ZNF550
    - 2.3.3.0.78 ZNF696
    - 2.3.3.0.79 ZNF263
    - 2.3.3.0.80 ZNF556
    - 2.3.3.0.81 ZNF192
    - 2.3.3.0.82 ZNF391
    - 2.3.3.0.83 ZNF239
    - 2.3.3.0.91 ZNF660
    - 2.3.3.0.92 GZF1
    - 2.3.3.0.93 ZNF408
    - 2.3.3.0.94 ZNF648
    - 2.3.3.0.95 ZNF768
    - 2.3.3.0.100 ZNF35
    - 2.3.3.0.101 ZNF483
    - 2.3.3.0.102 ZBTB48
    - 2.3.3.0.103 ZNF275
    - 2.3.3.0.104 ZIM3
    - 2.3.3.0.106 ZNF596
    - 2.3.3.0.111 ZNF718
    - 2.3.3.0.112 ZNF121
    - 2.3.3.0.113 ZNF485
    - 2.3.3.0.114 ZNF354C
    - 2.3.3.0.115 ZNF586
    - 2.3.3.0.118 ZNF10
    - 2.3.3.0.119 ZNF19
    - 2.3.3.0.123 ZBTB40
    - 2.3.3.0.124 ZBTB11
    - 2.3.3.0.125 ZNF454
    - 2.3.3.0.126 ZNF154
    - 2.3.3.0.127 ZNF416
    - 2.3.3.0.130 ZNF34
    - 2.3.3.0.136 ZNF320
    - 2.3.3.0.142 ZNF331
    - 2.3.3.0.148 ZNF329
    - 2.3.3.0.149 ZFP90
    - 2.3.3.0.150 ZNF317
    - 2.3.3.0.159 ZNF167
    - 2.3.3.0.160 ZNF250
    - 2.3.3.0.161 ZNF623
    - 2.3.3.0.162 ZFP3
    - 2.3.3.0.165 ZNF266
    - 2.3.3.0.166 ZNF311
    - 2.3.3.0.173 ZNF880
    - 2.3.3.0.174 ZNF287
    - 2.3.3.0.180 ZNF549
    - 2.3.3.0.183 ZNF676
    - 2.3.3.0.186 ZNF267
    - 2.3.3.0.191 ZNF471
    - 2.3.3.0.192 ZFP28
    - 2.3.3.0.193 ZNF182
    - 2.3.3.0.195 PRDM5
    - 2.3.3.0.196 RBAK
    - 2.3.3.0.197 ZNF189
    - 2.3.3.0.202 ZNF135
    - 2.3.3.0.210 ZNF23
    - 2.3.3.0.215 ZNF569
    - 2.3.3.0.216 ZNF84
    - 2.3.3.0.220 ZNF184
    - 2.3.3.0.221 ZNF441
    - 2.3.3.0.224 ZNF433
    - 2.3.3.0.225 ZNF337
    - 2.3.3.0.226 ZNF726
    - 2.3.3.0.227 ZNF624
    - 2.3.3.0.228 ZNF197
    - 2.3.3.0.232 ZNF594
    - 2.3.3.0.233 ZNF107
    - 2.3.3.0.234 ZNF208
    - 2.3.3.0 unclassified
    - 2.3.3.0.3 ZNF496
    - 2.3.3.0.6 ZNF274
    - 2.3.3.0.7 ZNF200
    - 2.3.3.0.9 OSR2
    - 2.3.3.0.16 ZNF793
    - 2.3.3.0.17 ZFP41
    - 2.3.3.0.18 ZNF215
    - 2.3.3.0.28 ZBTB44
    - 2.3.3.0.30 ZNF576
    - 2.3.3.0.40 ZNF394
    - 2.3.3.0.41 ZNF449
    - 2.3.3.0.42 ZNF498 (ZSCAN25)
    - 2.3.3.0.51 ZNF707
    - 2.3.3.0.60 ZNF202
    - 2.3.3.0.61 ZNF789
    - 2.3.3.0.62 ZNF662
    - 2.3.3.0.63 ZNF554
    - 2.3.3.0.64 ZNF506
    - 2.3.3.0.72 ZFP1
    - 2.3.3.0.74 ZBTB16
    - 2.3.3.0.75 GTF3A
    - 2.3.3.0.76 ZFP64
    - 2.3.3.0.77 ZNF358
    - 2.3.3.0.84 ZNF664
    - 2.3.3.0.87 ZNF501
    - 2.3.3.0.89 ZNF610
    - 2.3.3.0.96 ZNF517
    - 2.3.3.0.97 ZNF547
    - 2.3.3.0.98 ZNF766
    - 2.3.3.0.99 ZNF677
    - 2.3.3.0.109 ZNF682
    - 2.3.3.0.110 ZNF141
    - 2.3.3.0.120 ZSCAN12
    - 2.3.3.0.121 ZNF70
    - 2.3.3.0.122 ZNF79
    - 2.3.3.0.132 ZNF74
    - 2.3.3.0.133 ZNF415
    - 2.3.3.0.134 ZNF480
    - 2.3.3.0.143 ZNF461
    - 2.3.3.0.145 ZNF529
    - 2.3.3.0.146 ZNF565
    - 2.3.3.0.152 MZF1
    - 2.3.3.0.153 ZNF530
    - 2.3.3.0.156 ZNF695
    - 2.3.3.0.157 ZNF879
    - 2.3.3.0.158 ZNF790
    - 2.3.3.0.167 ZNF551
    - 2.3.3.0.168 ZNF497
    - 2.3.3.0.169 ZSCAN10
    - 2.3.3.0.175 ZNF502
    - 2.3.3.0.176 ZNF835
    - 2.3.3.0.177 ZNF560
    - 2.3.3.0.179 ZNF667
    - 2.3.3.0.188 ZNF83
    - 2.3.3.0.189 ZNF528
    - 2.3.3.0.190 ZNF7
    - 2.3.3.0.204 ZNF16
    - 2.3.3.0.205 ZNF17
    - 2.3.3.0.207 ZNF534
    - 2.3.3.0.209 ZNF791
    - 2.3.3.0.217 ZNF749
    - 2.3.3.0.218 ZNF425
    - 2.3.3.0.229 ZNF493
    - 2.3.3.0.230 ZNF43
    - 2.3.3.0.231 ZFP62
    - 2.3.3.0.235 ZNF91
  - 2.3.4 Factors with multiple dispersed zinc fingers
  - 2.3.5 BED zinc finger factors
- 2.5 DM-type intertwined zinc finger factors
- 2.6 CXXC zinc finger factors
- 2.7 C2HC
- 2.8 C3H zinc finger factors
- 2.9 C2CH THAP-type zinc finger factors
3 Helix-turn-helix domains
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 29

Species specific reports

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Ailuropoda melanoleuca

Synonyms: giant panda

Outlinks

Ensembl gene: ENSAMEG00000007380

Bos taurus

Synonyms: cattle, domestic cow

Outlinks

Ensembl gene: ENSBTAG00000003465

Callithrix jacchus

Synonyms: white-tufted-ear marmoset, white ear-tufted marmoset

Outlinks

Ensembl gene: ENSCJAG00000000347
UniProt: F7GSR9

Isoforms and DNA binding domain

Canis lupus familiaris

Synonyms: dog, dogs

Outlinks

Ensembl: ENSCAFG00000031863

Dasypus novemcinctus

Synonyms: nine-banded armadillo

Outlinks

Ensembl gene: ENSDNOG00000007169

Echinops telfairi

Synonyms: small Madagascar hedgehog, lesser hedgehog tenrec

Outlinks

Ensembl gene: ENSETEG00000012286
UniProt: NA

Equus caballus

Synonyms: horse, equine

Outlinks

Ensembl gene: ENSECAG00000002408

Erinaceus europaeus

Synonyms: western European hedgehog, common hedgehog

Outlinks

Ensembl gene: ENSEEUG00000007468
UniProt: NA

Felis catus

Synonyms: domestic cat, cats

Outlinks

Ensembl gene: ENSFCAG00000009828

Gorilla gorilla gorilla

Synonyms: western lowland gorilla, lowland gorilla

Outlinks

Ensembl gene: ENSGGOG00000002485

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000181894
Ensembl gene: ENSG00000181894
ProteinAtlas: ENSG00000181894 ( with antibody)
TRANSFAC: T20522
UniProt: Q86UD4

Protein expression pattern:Show tableIsoforms and DNA binding domain

Loxodonta africana

Synonyms: African savanna elephant, African savannah elephant

Outlinks

Ensembl gene: ENSLAFG00000009318
UniProt: NA

Macaca mulatta

Synonyms: Rhesus monkey, rhesus monkeys

Outlinks

Ensembl gene: ENSMMUG00000020504

Microcebus murinus

Synonyms: gray mouse lemur, grey mouse lemur

Outlinks

Ensembl: ENSMICG00000017854

Mus musculus

Synonyms: house mouse, mouse

Outlinks

Ensembl gene: ENSMUSG00000057894
TRANSFAC: T20524
UniProt: Q6GQR8

Isoforms and DNA binding domain

Mustela putorius furo

Synonyms: domestic ferret, ferret

Outlinks

Ensembl: ENSMPUG00000019115

Myotis lucifugus

Synonyms: little brown bat

Outlinks

Ensembl gene: ENSMLUG00000014403
UniProt: NA

Nomascus leucogenys

Synonyms: northern white-cheeked gibbon, White-cheeked Gibbon

Outlinks

Ensembl gene: ENSNLEG00000019190
UniProt: NA

Ochotona princeps

Synonyms: American pika, southern American pika

Outlinks

Ensembl gene: ENSOPRG00000007369
UniProt: NA

Oryctolagus cuniculus

Synonyms: rabbit, rabbits

Outlinks

Ensembl gene: ENSOCUG00000002886

Otolemur garnettii

Synonyms: small-eared galago

Outlinks

Ensembl gene: ENSOGAG00000005636

Pan troglodytes

Synonyms: chimpanzee

Outlinks

Ensembl gene: ENSPTRG00000011582
UniProt: H2R0U3

Isoforms and DNA binding domain

Pongo abelii

Synonyms: Sumatran orangutan, orang utan

Outlinks

Ensembl gene: ENSPPYG00000010492

Pteropus vampyrus

Synonyms: large flying fox

Outlinks

Ensembl gene: ENSPVAG00000002937
UniProt: NA

Rattus norvegicus

Synonyms: Norway rat, rats

Outlinks

Ensembl gene: ENSRNOG00000019376
UniProt: D4AA65

Isoforms and DNA binding domain

Sorex araneus

Synonyms: European shrew, Eurasian shrew

Outlinks

Ensembl gene: ENSSARG00000004583
UniProt: NA

Sus scrofa

Synonyms: pig, wild boar

Outlinks

Ensembl gene: ENSSSCG00000023027

Tarsius syrichta

Synonyms: Philippine tarsier

Outlinks

Ensembl: ENSTSYG00000003695

Vicugna pacos

Synonyms: alpaca

Outlinks

Ensembl gene: ENSVPAG00000010098
UniProt: NA

Select species

Selected the species for which a species report should be shown.

Ailuropoda melanoleuca, giant panda
Bos taurus, cattle
Callithrix jacchus, white-tufted-ear marmoset
Canis lupus familiaris, dog
Cavia porcellus, domestic guinea pig
Choloepus hoffmanni, Hoffmann's two-fingered sloth
Dasypus novemcinctus, nine-banded armadillo
Dipodomys ordii, Ord's kangaroo rat
Echinops telfairi, small Madagascar hedgehog
Equus caballus, horse
Erinaceus europaeus, western European hedgehog
Felis catus, domestic cat
Gorilla gorilla gorilla, western lowland gorilla
Homo sapiens, human
Ictidomys tridecemlineatus, thirteen-lined ground squirrel
Loxodonta africana, African savanna elephant
Macaca mulatta, Rhesus monkey
Macropus eugenii, tammar wallaby
Microcebus murinus, gray mouse lemur
Monodelphis domestica, gray short-tailed opossum
Mus musculus, house mouse
Mustela putorius furo, domestic ferret
Myotis lucifugus, little brown bat
Nomascus leucogenys, northern white-cheeked gibbon
Ochotona princeps, American pika
Ornithorhynchus anatinus, platypus
Oryctolagus cuniculus, rabbit
Otolemur garnettii, small-eared galago
Ovis aries, sheep
Pan troglodytes, chimpanzee
Pongo abelii, Sumatran orangutan
Procavia capensis, Cape rock hyrax
Pteropus vampyrus, large flying fox
Rattus norvegicus, Norway rat
Sarcophilus harrisii, Tasmanian devil
Sorex araneus, European shrew
Sus scrofa, pig
Tarsius syrichta, Philippine tarsier
Tupaia belangeri, northern tree shrew
Tursiops truncatus, bottlenose dolphin
Vicugna pacos, alpaca

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

pp12345pp

Tissue	Cell type	Expression level	Type	Reliability
adrenal gland	glandular tissue	Strong	Staining	Uncertain
appendix	glandular tissue	Strong	Staining	Uncertain
appendix	lymphoid tissue	Negative	Staining	Uncertain
bone barrow	hematopoetic stem cell	Weak	Staining	Uncertain
breast	glandular tissue	Moderate	Staining	Uncertain
bronchi	ciliated call with propulsive function of respiratory tract	Moderate	Staining	Uncertain
cerebellum	granule cell	Moderate	Staining	Uncertain
cerebellum		Negative	Staining	Uncertain
cerebellum	purkinje cell	Moderate	Staining	Uncertain
cerebral cortex	glial cell of central nervous system	Negative	Staining	Uncertain
cerebral cortex	neuron	Weak	Staining	Uncertain
cervix of uterus	glandular tissue	Moderate	Staining	Uncertain
cervix of uterus	squamous epithelial cell	Weak	Staining	Uncertain
colon	glandular tissue	Moderate	Staining	Uncertain
duodenum	glandular tissue	Moderate	Staining	Uncertain

pp12345pp

Classification of Transcription Factors in Mammalia

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Species specific reports

Classification of Transcription Factors in Mammalia

About TFClass

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Species specific reports

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