Classification of Transcription Factors in Mammalia

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1 Basic domains
- 1.1 Basic leucine zipper factors (bZIP)
- 1.2 Basic helix-loop-helix factors (bHLH)
  - 1.2.1 E2A
  - 1.2.2 MyoD-ASC-related
  - 1.2.3 Tal-related
    - 1.2.3.1 TAL-HEN
    - 1.2.3.2 TWIST
    - 1.2.3.3 MESP
    - 1.2.3.4 Neurogenin-ATO
      - 1.2.3.4.1 NEUROD1
      - 1.2.3.4.2 NEUROD2
      - 1.2.3.4.3 NEUROD4
      - 1.2.3.4.4 NEUROD6
      - 1.2.3.4.5 NGN1/NEUROG1
      - 1.2.3.4.6 NGN2/NEUROG2
      - 1.2.3.4.7 NGN3/NEUROG3
      - 1.2.3.4.8 ATOH1
      - 1.2.3.4.9 ATOH7
      - 1.2.3.4.10 ATOH8
      - 1.2.3.4.11 BHLHE22
      - 1.2.3.4.12 BHLHE23
      - 1.2.3.4.13 OLIG1
      - 1.2.3.4.14 OLIG2
      - 1.2.3.4.15 OLIG3
      - 1.2.3.4.16 BHLHA15
      - 1.2.3.4.17 FERD3L
    - 1.2.3.5 BHLHA9
  - 1.2.4 Hairy-related
  - 1.2.5 PAS
  - 1.2.6 bHLH-ZIP
  - 1.2.8 HLH only
- 1.3 Basic helix-span-helix factors (bHSH)
2 Zinc-coordinating DNA-binding domains
3 Helix-turn-helix domains
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 25 LOGO plot of the DNA binding sequence

Species specific reports

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Bos taurus

Synonyms: cattle, domestic cow

Outlinks

Ensembl gene: ENSBTAG00000046010

Callithrix jacchus

Synonyms: white-tufted-ear marmoset, white ear-tufted marmoset

Outlinks

Ensembl gene: ENSCJAG00000023085

Canis lupus familiaris

Synonyms: dog, dogs

Outlinks

Ensembl: ENSCAFG00000015425

Cavia porcellus

Synonyms: domestic guinea pig, guinea pig

Outlinks

Ensembl: ENSCPOG00000009423

Equus caballus

Synonyms: horse, equine

Outlinks

Ensembl gene: ENSECAG00000012532

Felis catus

Synonyms: domestic cat, cats

Outlinks

Ensembl gene: ENSFCAG00000000315

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000180535
Ensembl gene: ENSG00000180535
ProteinAtlas: ENSG00000180535 ( with antibody)
TRANSFAC: T23535
UniProt: Q7RTS1

Isoforms and DNA binding domain

Ictidomys tridecemlineatus

Synonyms: thirteen-lined ground squirrel

Outlinks

Ensembl gene: ENSSTOG00000009728
UniProt: NA

Loxodonta africana

Synonyms: African savanna elephant, African savannah elephant

Outlinks

Ensembl gene: ENSLAFG00000000139
UniProt: NA

Macaca mulatta

Synonyms: Rhesus monkey, rhesus monkeys

Outlinks

Ensembl: ENSMMUG00000015478

Monodelphis domestica

Synonyms: gray short-tailed opossum

Outlinks

Ensembl gene: ENSMODG00000025044
UniProt: NA

Mus musculus

Synonyms: house mouse, mouse

Outlinks

Ensembl gene: ENSMUSG00000052271
TRANSFAC: T
UniProt: Q9QYC3

Isoforms and DNA binding domain

Mustela putorius furo

Synonyms: domestic ferret, ferret

Outlinks

Ensembl: ENSMPUG00000020102

Myotis lucifugus

Synonyms: little brown bat

Outlinks

Ensembl gene: ENSMLUG00000009476
UniProt: NA

Nomascus leucogenys

Synonyms: northern white-cheeked gibbon, White-cheeked Gibbon

Outlinks

Ensembl gene: ENSNLEG00000018875
UniProt: NA

Ornithorhynchus anatinus

Synonyms: platypus, duckbill platypus

Outlinks

Ensembl gene: ENSOANG00000001937
UniProt: NA

Oryctolagus cuniculus

Synonyms: rabbit, rabbits

Outlinks

Ensembl gene: ENSOCUG00000025058

Otolemur garnettii

Synonyms: small-eared galago

Outlinks

Ensembl gene: ENSOGAG00000010106

Pan troglodytes

Synonyms: chimpanzee

Outlinks

Ensembl gene: ENSPTRG00000019434

Pongo abelii

Synonyms: Sumatran orangutan, orang utan

Outlinks

Ensembl gene: ENSPPYG00000017361

Rattus norvegicus

Synonyms: Norway rat, rats

Outlinks

Ensembl gene: ENSRNOG00000025164
UniProt: P70562

Isoforms and DNA binding domain

Sarcophilus harrisii

Synonyms: Tasmanian devil

Outlinks

Ensembl gene: ENSSHAG00000015620
UniProt: NA

Sorex araneus

Synonyms: European shrew, Eurasian shrew

Outlinks

Ensembl gene: ENSSARG00000005281
UniProt: NA

Sus scrofa

Synonyms: pig, wild boar

Outlinks

Ensembl: ENSSSCG00000007600

Tursiops truncatus

Synonyms: bottlenose dolphin, bottle-nosed dolphin

Outlinks

Ensembl gene: ENSTTRG00000015701
UniProt: NA