Transcription factor classification

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1 Basic domains
2 Zinc-coordinating DNA-binding domains
- 2.1 Nuclear receptors with C4 zinc fingers
- 2.2 Other C4 zinc finger-type factors
- 2.3 C2H2 zinc finger factors
  - 2.3.1 Three-zinc finger Krüppel-related
  - 2.3.2 Other factors with up to three adjacent zinc fingers
  - 2.3.3 More than 3 adjacent zinc fingers
  - 2.3.4 Factors with multiple dispersed zinc fingers
    - 2.3.4.1 ZNF417-like
    - 2.3.4.2 ZNF219-like
    - 2.3.4.3 SAL-like
    - 2.3.4.4 Ikaros
    - 2.3.4.5 HIV EP
    - 2.3.4.6 ZBTB1-like
    - 2.3.4.7 RLF-like
    - 2.3.4.8 MAZ-like
    - 2.3.4.9 ZNF532-like
    - 2.3.4.10 ZNF512
    - 2.3.4.11 ZNF658
    - 2.3.4.12 ZNF423-like
    - 2.3.4.13 ZNF639-like
    - 2.3.4.14 EVI1-like
    - 2.3.4.15 BCL11
    - 2.3.4.16 Insulinoma-associated proteins
    - 2.3.4.17 HIC
    - 2.3.4.18 ZNF518
    - 2.3.4.19 Basonuclin
    - 2.3.4.20 TRERF1-like
    - 2.3.4.21 HINFP-like
    - 2.3.4.22 ZNF526-like
    - 2.3.4.23 ZNF319-like
    - 2.3.4.24 ZNF134-like
    - 2.3.4.25 ZNF37A-like
    - 2.3.4.0.1 CASZ1
    - 2.3.4.0.2 ZNF335
    - 2.3.4.0.4 WIZ
    - 2.3.4.0.5 ZNF469
    - 2.3.4.0.6 ZFPM1
    - 2.3.4.0.7 ZBTB4
    - 2.3.4.0.9 ZBTB39
    - 2.3.4.0.10 ZNF295
    - 2.3.4.0.12 PRDM13
    - 2.3.4.0.13 ZNF646
    - 2.3.4.0.14 ZNF579
    - 2.3.4.0.16 PRDM2
    - 2.3.4.0.17 ZNF800
    - 2.3.4.0.18 ZNF618
    - 2.3.4.0.21 ZNF451
    - 2.3.4.0.22 ZNF438
    - 2.3.4.0.24 ZNF507
    - 2.3.4.0.25 ZNF236
    - 2.3.4.0.26 ZNF770
    - 2.3.4.0.28 ZFP57
    - 2.3.4.0.30 ZNF597
    - 2.3.4.0.32 PRDM15
    - 2.3.4.0.33 ZBTB41
    - 2.3.4.0.34 PRDM10
    - 2.3.4.0.36 ZNF513
    - 2.3.4.0.37 ZNF142
    - 2.3.4.0.38 FIZ1
    - 2.3.4.0.40 ZNF784
    - 2.3.4.0.41 ZNF697
    - 2.3.4.0.42 ZKSCAN5
    - 2.3.4.0.44 ZNF775
    - 2.3.4.0.45 ZNF467
    - 2.3.4.0.46 ZNF787
    - 2.3.4.0.48 ZNF48
    - 2.3.4.0.49 ZNF629
    - 2.3.4.0.50 ZNF668
    - 2.3.4.0.51 ZNF101
    - 2.3.4.0.52 ZNF251
    - 2.3.4.0.53 ZNF445
    - 2.3.4.0.56 ZSCAN20
    - 2.3.4.0.57 ZNF674
    - 2.3.4.0.60 ZNF788
    - 2.3.4.0.63 ZNF778
    - 2.3.4.0.68 ZNF519
    - 2.3.4.0.69 ZNF304
    - 2.3.4.0.70 ZNF132
    - 2.3.4.0.72 ZBTB17
    - 2.3.4.0.73 ZNF407
    - 2.3.4.0.74 E4F1
    - 2.3.4.0 unclassified
    - 2.3.4.0.3 PRDM8
    - 2.3.4.0.8 ZBTB38
    - 2.3.4.0.15 RREB1
    - 2.3.4.0.19 ZNF277
    - 2.3.4.0.23 PEG3
    - 2.3.4.0.27 REST
    - 2.3.4.0.31 PRDM4
    - 2.3.4.0.35 ZNF341
    - 2.3.4.0.39 ZNF628
    - 2.3.4.0.43 ZNF316
    - 2.3.4.0.59 ZNF195
    - 2.3.4.0.67 ZNF606
    - 2.3.4.0.71 PRDM9
    - 2.3.4.0.75 ZNF462
    - 2.3.4.0.76 ZNF644
  - 2.3.5 BED zinc finger factors
- 2.5 DM-type intertwined zinc finger factors
- 2.6 CXXC zinc finger factors
- 2.7 C2HC
- 2.8 C3H zinc finger factors
- 2.9 C2CH THAP-type zinc finger factors
3 Helix-turn-helix domains
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains