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Classification of Transcription Factors in Mammalia

About TFClass

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Family:

, Subfamily:

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1 Basic domains
2 Zinc-coordinating DNA-binding domains
3 Helix-turn-helix domains
- 3.1 Homeo domain factors
- 3.2 Paired box factors
- 3.3 Fork head / winged helix factors
- 3.4 Heat shock factors
- 3.5 Tryptophan cluster factors
- 3.6 TEA domain factors
- 3.7 ARID
  - 3.7.1 ARID-related
    - 3.7.1.1 ARID1
    - 3.7.1.2 ARID2
    - 3.7.1.3 ARID3
      - 3.7.1.3.1 ARID3A
    - 3.7.1.4 ARID4
    - 3.7.1.5 ARID5
    - 3.7.1.6 JARID1
    - 3.7.1.7 JARID2
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 36

Species specific reports

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Ailuropoda melanoleuca

Synonyms: giant panda

Outlinks

Ensembl gene: ENSAMEG00000009014
UniProt: D2HKY8

Isoforms and DNA binding domain

Bos taurus

Synonyms: cattle, domestic cow

Outlinks

Ensembl gene: ENSBTAG00000025792
Ensembl gene: ENSBTAG00000008607
Ensembl gene: ENSBTAG00000011828

Callithrix jacchus

Synonyms: white-tufted-ear marmoset, white ear-tufted marmoset

Outlinks

Ensembl gene: ENSCJAG00000020111
Ensembl gene: ENSCJAG00000017758
Ensembl gene: ENSCJAG00000008754

Canis lupus familiaris

Synonyms: dog, dogs

Outlinks

Cavia porcellus

Synonyms: domestic guinea pig, guinea pig

Outlinks

Ensembl gene: ENSCPOG00000011820
Ensembl gene: ENSCPOG00000012901
Ensembl gene: ENSCPOG00000001541

Choloepus hoffmanni

Synonyms: Hoffmann's two-fingered sloth, Hoffmann's two-toed sloth

Outlinks

Ensembl gene: ENSCHOG00000011584
UniProt: NA

Dasypus novemcinctus

Synonyms: nine-banded armadillo

Outlinks

Ensembl gene: ENSDNOG00000030859
Ensembl gene: ENSDNOG00000042496
Ensembl gene: ENSDNOG00000033442

Dipodomys ordii

Synonyms: Ord's kangaroo rat

Outlinks

Ensembl gene: ENSDORG00000012637
Ensembl gene: ENSDORG00000001723
UniProt: NA

Equus caballus

Synonyms: horse, equine

Outlinks

Ensembl gene: ENSECAG00000013123
Ensembl gene: ENSECAG00000019080
Ensembl gene: ENSECAG00000011779

Felis catus

Synonyms: domestic cat, cats

Outlinks

Ensembl gene: ENSFCAG00000002012
Ensembl gene: ENSFCAG00000003156
Ensembl gene: ENSFCAG00000027384

Gorilla gorilla gorilla

Synonyms: western lowland gorilla, lowland gorilla

Outlinks

Ensembl gene: ENSGGOG00000002920
Ensembl gene: ENSGGOG00000000602
Ensembl gene: ENSGGOG00000001766

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000116017
Ensembl gene: ENSG00000116017
Ensembl gene: ENSG00000179361
Ensembl gene: ENSG00000205143
ProteinAtlas: ENSG00000116017 ( with antibody)
TRANSFAC: T04867
UniProt: Q8IVW6
UniProt: Q99856

Protein expression pattern:Show tableIsoforms and DNA binding domain

Ictidomys tridecemlineatus

Synonyms: thirteen-lined ground squirrel

Outlinks

Ensembl gene: ENSSTOG00000002820
Ensembl gene: ENSSTOG00000013927
Ensembl gene: ENSSTOG00000006037
UniProt: NA

Loxodonta africana

Synonyms: African savanna elephant, African savannah elephant

Outlinks

Ensembl gene: ENSLAFG00000005629
Ensembl gene: ENSLAFG00000002987
Ensembl gene: ENSLAFG00000017911
UniProt: NA

Macaca mulatta

Synonyms: Rhesus monkey, rhesus monkeys

Outlinks

Ensembl gene: ENSMMUG00000020786
Ensembl gene: ENSMMUG00000001568

Macropus eugenii

Synonyms: tammar wallaby

Outlinks

Microcebus murinus

Synonyms: gray mouse lemur, grey mouse lemur

Outlinks

Ensembl gene: ENSMICG00000010143
UniProt: NA

Monodelphis domestica

Synonyms: gray short-tailed opossum

Outlinks

Ensembl gene: ENSMODG00000005667
Ensembl gene: ENSMODG00000027824
Ensembl gene: ENSMODG00000009472
UniProt: NA

Mus musculus

Synonyms: house mouse, mouse

Outlinks

Ensembl gene: ENSMUSG00000019564
Ensembl gene: ENSMUSG00000066224
Ensembl gene: ENSMUSG00000004661
TRANSFAC: T06432
UniProt: Q62431
UniProt: Q9Z1N7
UniProt: A6PWV5

Isoforms and DNA binding domain

Mustela putorius furo

Synonyms: domestic ferret, ferret

Outlinks

Myotis lucifugus

Synonyms: little brown bat

Outlinks

Ensembl gene: ENSMLUG00000011678
Ensembl gene: ENSMLUG00000022582
Ensembl gene: ENSMLUG00000013261
UniProt: NA

Nomascus leucogenys

Synonyms: northern white-cheeked gibbon, White-cheeked Gibbon

Outlinks

Ensembl gene: ENSNLEG00000014530
Ensembl gene: ENSNLEG00000004860
UniProt: NA

Ochotona princeps

Synonyms: American pika, southern American pika

Outlinks

Ensembl gene: ENSOPRG00000007538
Ensembl gene: ENSOPRG00000009210
Ensembl gene: ENSOPRG00000002281
UniProt: NA

Ornithorhynchus anatinus

Synonyms: platypus, duckbill platypus

Outlinks

Ensembl gene: ENSOANG00000010382
Ensembl gene: ENSOANG00000009382
Ensembl gene: ENSOANG00000012252
UniProt: NA

Oryctolagus cuniculus

Synonyms: rabbit, rabbits

Outlinks

Ensembl gene: ENSOCUG00000000361
Ensembl gene: ENSOCUG00000025077

Otolemur garnettii

Synonyms: small-eared galago

Outlinks

Ensembl gene: ENSOGAG00000008253
Ensembl gene: ENSOGAG00000013680
Ensembl gene: ENSOGAG00000014431

Ovis aries

Synonyms: sheep, wild sheep

Outlinks

Ensembl gene: ENSOARG00000018054
Ensembl gene: ENSOARG00000003574
Ensembl gene: ENSOARG00000009192
Ensembl gene: ENSOARG00000010130

Pan troglodytes

Synonyms: chimpanzee

Outlinks

Ensembl gene: ENSPTRG00000029286
Ensembl gene: ENSPTRG00000010173
Ensembl gene: ENSPTRG00000007277

Pongo abelii

Synonyms: Sumatran orangutan, orang utan

Outlinks

Ensembl gene: ENSPPYG00000009299
Ensembl gene: ENSPPYG00000020014
Ensembl gene: ENSPPYG00000006640

Pteropus vampyrus

Synonyms: large flying fox

Outlinks

Ensembl gene: ENSPVAG00000014726
Ensembl gene: ENSPVAG00000014819
UniProt: NA

Rattus norvegicus

Synonyms: Norway rat, rats

Outlinks

Ensembl gene: ENSRNOG00000013416
Ensembl gene: ENSRNOG00000019677
Ensembl gene: ENSRNOG00000026435
UniProt: B5DEX9
UniProt: D3ZGC2

Isoforms and DNA binding domain

Sarcophilus harrisii

Synonyms: Tasmanian devil

Outlinks

Ensembl gene: ENSSHAG00000014608
Ensembl gene: ENSSHAG00000013317
Ensembl gene: ENSSHAG00000017446
UniProt: NA

Sus scrofa

Synonyms: pig, wild boar

Outlinks

Tupaia belangeri

Synonyms: northern tree shrew, common tree shrew

Outlinks

Ensembl gene: ENSTBEG00000004554
UniProt: NA

Tursiops truncatus

Synonyms: bottlenose dolphin, bottle-nosed dolphin

Outlinks

Ensembl gene: ENSTTRG00000001472
Ensembl gene: ENSTTRG00000007975
Ensembl gene: ENSTTRG00000005673
UniProt: NA

Vicugna pacos

Synonyms: alpaca

Outlinks

Ensembl gene: ENSVPAG00000003483
UniProt: NA

Select species

Selected the species for which a species report should be shown.

Ailuropoda melanoleuca, giant panda
Bos taurus, cattle
Callithrix jacchus, white-tufted-ear marmoset
Canis lupus familiaris, dog
Cavia porcellus, domestic guinea pig
Choloepus hoffmanni, Hoffmann's two-fingered sloth
Dasypus novemcinctus, nine-banded armadillo
Dipodomys ordii, Ord's kangaroo rat
Echinops telfairi, small Madagascar hedgehog
Equus caballus, horse
Erinaceus europaeus, western European hedgehog
Felis catus, domestic cat
Gorilla gorilla gorilla, western lowland gorilla
Homo sapiens, human
Ictidomys tridecemlineatus, thirteen-lined ground squirrel
Loxodonta africana, African savanna elephant
Macaca mulatta, Rhesus monkey
Macropus eugenii, tammar wallaby
Microcebus murinus, gray mouse lemur
Monodelphis domestica, gray short-tailed opossum
Mus musculus, house mouse
Mustela putorius furo, domestic ferret
Myotis lucifugus, little brown bat
Nomascus leucogenys, northern white-cheeked gibbon
Ochotona princeps, American pika
Ornithorhynchus anatinus, platypus
Oryctolagus cuniculus, rabbit
Otolemur garnettii, small-eared galago
Ovis aries, sheep
Pan troglodytes, chimpanzee
Pongo abelii, Sumatran orangutan
Procavia capensis, Cape rock hyrax
Pteropus vampyrus, large flying fox
Rattus norvegicus, Norway rat
Sarcophilus harrisii, Tasmanian devil
Sorex araneus, European shrew
Sus scrofa, pig
Tarsius syrichta, Philippine tarsier
Tupaia belangeri, northern tree shrew
Tursiops truncatus, bottlenose dolphin
Vicugna pacos, alpaca

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

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Tissue	Cell type	Expression level	Type	Reliability
adrenal gland	glandular tissue	Negative	Staining	Uncertain
appendix	glandular tissue	Negative	Staining	Uncertain
appendix	lymphoid tissue	Weak	Staining	Uncertain
bone barrow	hematopoetic stem cell	Strong	Staining	Uncertain
breast	glandular tissue	Weak	Staining	Uncertain
bronchi	ciliated call with propulsive function of respiratory tract	Weak	Staining	Uncertain
cerebellum	granule cell	Negative	Staining	Uncertain
cerebellum		Negative	Staining	Uncertain
cerebellum	purkinje cell	Negative	Staining	Uncertain
cerebral cortex	glial cell of central nervous system	Negative	Staining	Uncertain
cerebral cortex	neuron	Negative	Staining	Uncertain
cervix of uterus	glandular tissue	Weak	Staining	Uncertain
cervix of uterus	squamous epithelial cell	Negative	Staining	Uncertain
colon	glandular tissue	Negative	Staining	Uncertain
duodenum	glandular tissue	Weak	Staining	Uncertain

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