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Classification of Transcription Factors in Mammalia

About TFClass

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Superclass:

, Class:

,
Family:

, Subfamily:

, Genus:

,

1 Basic domains
- 1.1 Basic leucine zipper factors (bZIP)
  - 1.1.1 Jun-related
  - 1.1.2 Fos-related
  - 1.1.3 Maf-related
    - 1.1.3.1 Large MAF
    - 1.1.3.2 Small MAF
      - 1.1.3.2.1 MAFF
      - 1.1.3.2.2 MAFG
      - 1.1.3.2.3 MAFK
  - 1.1.4 B-ATF-related
  - 1.1.5 XBP1-related
  - 1.1.6 ATF4-related
  - 1.1.7 CREB-related
  - 1.1.8 CEBP-related
- 1.2 Basic helix-loop-helix factors (bHLH)
- 1.3 Basic helix-span-helix factors (bHSH)
2 Zinc-coordinating DNA-binding domains
3 Helix-turn-helix domains
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 28 LOGO plot of the DNA binding sequence

Species specific reports

Jump to human, mouse or rat
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Bos taurus

Synonyms: cattle, domestic cow

Outlinks

Ensembl gene: ENSBTAG00000019303

Canis lupus familiaris

Synonyms: dog, dogs

Outlinks

Ensembl: ENSCAFG00000016491

Cavia porcellus

Synonyms: domestic guinea pig, guinea pig

Outlinks

Ensembl: ENSCPOG00000025240

Dasypus novemcinctus

Synonyms: nine-banded armadillo

Outlinks

Ensembl gene: ENSDNOG00000025336

Dipodomys ordii

Synonyms: Ord's kangaroo rat

Outlinks

Ensembl: ENSDORG00000006881

Echinops telfairi

Synonyms: small Madagascar hedgehog, lesser hedgehog tenrec

Outlinks

Ensembl gene: ENSETEG00000019615
UniProt: NA

Erinaceus europaeus

Synonyms: western European hedgehog, common hedgehog

Outlinks

Ensembl gene: ENSEEUG00000015865
Ensembl gene: ENSEEUG00000001564
UniProt: NA

Gorilla gorilla gorilla

Synonyms: western lowland gorilla, lowland gorilla

Outlinks

Ensembl gene: ENSGGOG00000013970

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000198517
Ensembl gene: ENSG00000198517
ProteinAtlas: ENSG00000198517 ( with antibody)
TRANSFAC: T04874
UniProt: O60675

Protein expression pattern:Show tableIsoforms and DNA binding domain

Ictidomys tridecemlineatus

Synonyms: thirteen-lined ground squirrel

Outlinks

Ensembl gene: ENSSTOG00000028786
UniProt: NA

Loxodonta africana

Synonyms: African savanna elephant, African savannah elephant

Outlinks

Ensembl gene: ENSLAFG00000026184
UniProt: NA

Macaca mulatta

Synonyms: Rhesus monkey, rhesus monkeys

Outlinks

Ensembl: ENSMMUG00000013077

Macropus eugenii

Synonyms: tammar wallaby

Outlinks

Ensembl: ENSMEUG00000006741

Microcebus murinus

Synonyms: gray mouse lemur, grey mouse lemur

Outlinks

Ensembl: ENSMICG00000016881

Monodelphis domestica

Synonyms: gray short-tailed opossum

Outlinks

Ensembl gene: ENSMODG00000009013
UniProt: NA

Mus musculus

Synonyms: house mouse, mouse

Outlinks

Ensembl gene: ENSMUSG00000018143
TRANSFAC: T01435
UniProt: Q61827

Isoforms and DNA binding domain

Mustela putorius furo

Synonyms: domestic ferret, ferret

Outlinks

Ensembl: ENSMPUG00000017907

Nomascus leucogenys

Synonyms: northern white-cheeked gibbon, White-cheeked Gibbon

Outlinks

Ensembl gene: ENSNLEG00000008578
UniProt: NA

Ochotona princeps

Synonyms: American pika, southern American pika

Outlinks

Ensembl gene: ENSOPRG00000017005
UniProt: NA

Ornithorhynchus anatinus

Synonyms: platypus, duckbill platypus

Outlinks

Ensembl gene: ENSOANG00000014931
UniProt: NA

Otolemur garnettii

Synonyms: small-eared galago

Outlinks

Ensembl gene: ENSOGAG00000000377

Pongo abelii

Synonyms: Sumatran orangutan, orang utan

Outlinks

Ensembl: ENSCJAG00000001481
Ensembl gene: ENSPPYG00000017301

Procavia capensis

Synonyms: Cape rock hyrax, rock hyrax

Outlinks

Ensembl gene: ENSPCAG00000015313
UniProt: NA

Pteropus vampyrus

Synonyms: large flying fox

Outlinks

Ensembl gene: ENSPVAG00000013872
UniProt: NA

Rattus norvegicus

Synonyms: Norway rat, rats

Outlinks

Ensembl gene: ENSRNOG00000001277
UniProt: Q6IRI7

Isoforms and DNA binding domain

Sarcophilus harrisii

Synonyms: Tasmanian devil

Outlinks

Ensembl gene: ENSSHAG00000011447
UniProt: NA

Sus scrofa

Synonyms: pig, wild boar

Outlinks

Ensembl gene: ENSSSCG00000007559

Tupaia belangeri

Synonyms: northern tree shrew, common tree shrew

Outlinks

Ensembl gene: ENSTBEG00000008165
UniProt: NA

Select species

Selected the species for which a species report should be shown.

Ailuropoda melanoleuca, giant panda
Bos taurus, cattle
Callithrix jacchus, white-tufted-ear marmoset
Canis lupus familiaris, dog
Cavia porcellus, domestic guinea pig
Choloepus hoffmanni, Hoffmann's two-fingered sloth
Dasypus novemcinctus, nine-banded armadillo
Dipodomys ordii, Ord's kangaroo rat
Echinops telfairi, small Madagascar hedgehog
Equus caballus, horse
Erinaceus europaeus, western European hedgehog
Felis catus, domestic cat
Gorilla gorilla gorilla, western lowland gorilla
Homo sapiens, human
Ictidomys tridecemlineatus, thirteen-lined ground squirrel
Loxodonta africana, African savanna elephant
Macaca mulatta, Rhesus monkey
Macropus eugenii, tammar wallaby
Microcebus murinus, gray mouse lemur
Monodelphis domestica, gray short-tailed opossum
Mus musculus, house mouse
Mustela putorius furo, domestic ferret
Myotis lucifugus, little brown bat
Nomascus leucogenys, northern white-cheeked gibbon
Ochotona princeps, American pika
Ornithorhynchus anatinus, platypus
Oryctolagus cuniculus, rabbit
Otolemur garnettii, small-eared galago
Ovis aries, sheep
Pan troglodytes, chimpanzee
Pongo abelii, Sumatran orangutan
Procavia capensis, Cape rock hyrax
Pteropus vampyrus, large flying fox
Rattus norvegicus, Norway rat
Sarcophilus harrisii, Tasmanian devil
Sorex araneus, European shrew
Sus scrofa, pig
Tarsius syrichta, Philippine tarsier
Tupaia belangeri, northern tree shrew
Tursiops truncatus, bottlenose dolphin
Vicugna pacos, alpaca

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

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Tissue	Cell type	Expression level	Type	Reliability
adrenal gland	glandular tissue	Negative	Staining	Supportive
appendix	glandular tissue	Negative	Staining	Supportive
appendix	lymphoid tissue	Negative	Staining	Supportive
bone barrow	hematopoetic stem cell	Weak	Staining	Supportive
breast	glandular tissue	Negative	Staining	Supportive
bronchi	ciliated call with propulsive function of respiratory tract	Negative	Staining	Supportive
cerebellum	granule cell	Negative	Staining	Supportive
cerebellum		Negative	Staining	Supportive
cerebellum	purkinje cell	Negative	Staining	Supportive
cerebral cortex	glial cell of central nervous system	Negative	Staining	Supportive
cerebral cortex	neuron	Negative	Staining	Supportive
cervix of uterus	glandular tissue	Negative	Staining	Supportive
cervix of uterus	squamous epithelial cell	Negative	Staining	Supportive
colon	glandular tissue	Weak	Staining	Supportive
duodenum	glandular tissue	Negative	Staining	Supportive

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