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Classification of Transcription Factors in Mammalia

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1 Basic domains
2 Zinc-coordinating DNA-binding domains
3 Helix-turn-helix domains
- 3.1 Homeo domain factors
- 3.2 Paired box factors
- 3.3 Fork head / winged helix factors
  - 3.3.1 FOX
    - 3.3.1.1 FOXA
    - 3.3.1.2 FOXB
    - 3.3.1.3 FOXC
    - 3.3.1.4 FOXD
    - 3.3.1.5 FOXE
    - 3.3.1.6 FOXF
      - 3.3.1.6.1 FOXF1
      - 3.3.1.6.2 FOXF2
    - 3.3.1.7 FOXG
    - 3.3.1.8 FOXH
    - 3.3.1.9 FOXI
    - 3.3.1.10 FOXJ
    - 3.3.1.11 FOXK
    - 3.3.1.12 FOXL
    - 3.3.1.13 FOXM
    - 3.3.1.14 FOXN
    - 3.3.1.15 FOXO
    - 3.3.1.16 FOXP
    - 3.3.1.17 FOXQ
    - 3.3.1.18 FOXR
    - 3.3.1.19 FOXS
  - 3.3.2 E2F
  - 3.3.3 RFX
- 3.4 Heat shock factors
- 3.5 Tryptophan cluster factors
- 3.6 TEA domain factors
- 3.7 ARID
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 27

Species specific reports

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Ailuropoda melanoleuca

Synonyms: giant panda

Outlinks

Ensembl gene: ENSAMEG00000018266

Bos taurus

Synonyms: cattle, domestic cow

Outlinks

Ensembl gene: ENSBTAG00000000009

Callithrix jacchus

Synonyms: white-tufted-ear marmoset, white ear-tufted marmoset

Outlinks

Ensembl gene: ENSCJAG00000017152

Canis lupus familiaris

Synonyms: dog, dogs

Outlinks

Ensembl: ENSCAFG00000019918

Cavia porcellus

Synonyms: domestic guinea pig, guinea pig

Outlinks

Ensembl gene: ENSCPOG00000000954

Equus caballus

Synonyms: horse, equine

Outlinks

Ensembl gene: ENSECAG00000020094

Erinaceus europaeus

Synonyms: western European hedgehog, common hedgehog

Outlinks

Ensembl gene: ENSEEUG00000002843
UniProt: NA

Gorilla gorilla gorilla

Synonyms: western lowland gorilla, lowland gorilla

Outlinks

Ensembl gene: ENSGGOG00000025357

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000103241
Ensembl gene: ENSG00000103241
ProteinAtlas: ENSG00000103241 ( with antibody)
TRANSFAC: T02464
UniProt: Q12946

Protein expression pattern:Show tableIsoforms and DNA binding domain

Loxodonta africana

Synonyms: African savanna elephant, African savannah elephant

Outlinks

Ensembl gene: ENSLAFG00000002036
UniProt: NA

Macaca mulatta

Synonyms: Rhesus monkey, rhesus monkeys

Outlinks

Ensembl: ENSMMUG00000019503

Macropus eugenii

Synonyms: tammar wallaby

Outlinks

Ensembl: ENSMEUG00000014695

Microcebus murinus

Synonyms: gray mouse lemur, grey mouse lemur

Outlinks

Ensembl: ENSMICG00000010236

Monodelphis domestica

Synonyms: gray short-tailed opossum

Outlinks

Ensembl gene: ENSMODG00000004542
UniProt: NA

Mus musculus

Synonyms: house mouse, mouse

Outlinks

Ensembl gene: ENSMUSG00000042812
TRANSFAC: T02461
UniProt: Q61080

Isoforms and DNA binding domain

Mustela putorius furo

Synonyms: domestic ferret, ferret

Outlinks

Ensembl: ENSMPUG00000008619

Nomascus leucogenys

Synonyms: northern white-cheeked gibbon, White-cheeked Gibbon

Outlinks

Ensembl gene: ENSNLEG00000011449
UniProt: NA

Ornithorhynchus anatinus

Synonyms: platypus, duckbill platypus

Outlinks

Ensembl gene: ENSOANG00000007633
UniProt: NA

Oryctolagus cuniculus

Synonyms: rabbit, rabbits

Outlinks

Ensembl gene: ENSOCUG00000001701

Otolemur garnettii

Synonyms: small-eared galago

Outlinks

Ensembl gene: ENSOGAG00000011910

Ovis aries

Synonyms: sheep, wild sheep

Outlinks

Ensembl gene: ENSOARG00000011547

Pan troglodytes

Synonyms: chimpanzee

Outlinks

Ensembl gene: ENSPTRG00000008439

Pongo abelii

Synonyms: Sumatran orangutan, orang utan

Outlinks

Ensembl gene: ENSPPYG00000007623

Procavia capensis

Synonyms: Cape rock hyrax, rock hyrax

Outlinks

Ensembl gene: ENSPCAG00000004953
UniProt: NA

Pteropus vampyrus

Synonyms: large flying fox

Outlinks

Ensembl gene: ENSPVAG00000007544
UniProt: NA

Rattus norvegicus

Synonyms: Norway rat, rats

Outlinks

Ensembl gene: ENSRNOG00000049906
UniProt: M0R8R8

Isoforms and DNA binding domain

Sarcophilus harrisii

Synonyms: Tasmanian devil

Outlinks

Ensembl gene: ENSSHAG00000012906
UniProt: NA

Select species

Selected the species for which a species report should be shown.

Ailuropoda melanoleuca, giant panda
Bos taurus, cattle
Callithrix jacchus, white-tufted-ear marmoset
Canis lupus familiaris, dog
Cavia porcellus, domestic guinea pig
Choloepus hoffmanni, Hoffmann's two-fingered sloth
Dasypus novemcinctus, nine-banded armadillo
Dipodomys ordii, Ord's kangaroo rat
Echinops telfairi, small Madagascar hedgehog
Equus caballus, horse
Erinaceus europaeus, western European hedgehog
Felis catus, domestic cat
Gorilla gorilla gorilla, western lowland gorilla
Homo sapiens, human
Ictidomys tridecemlineatus, thirteen-lined ground squirrel
Loxodonta africana, African savanna elephant
Macaca mulatta, Rhesus monkey
Macropus eugenii, tammar wallaby
Microcebus murinus, gray mouse lemur
Monodelphis domestica, gray short-tailed opossum
Mus musculus, house mouse
Mustela putorius furo, domestic ferret
Myotis lucifugus, little brown bat
Nomascus leucogenys, northern white-cheeked gibbon
Ochotona princeps, American pika
Ornithorhynchus anatinus, platypus
Oryctolagus cuniculus, rabbit
Otolemur garnettii, small-eared galago
Ovis aries, sheep
Pan troglodytes, chimpanzee
Pongo abelii, Sumatran orangutan
Procavia capensis, Cape rock hyrax
Pteropus vampyrus, large flying fox
Rattus norvegicus, Norway rat
Sarcophilus harrisii, Tasmanian devil
Sorex araneus, European shrew
Sus scrofa, pig
Tarsius syrichta, Philippine tarsier
Tupaia belangeri, northern tree shrew
Tursiops truncatus, bottlenose dolphin
Vicugna pacos, alpaca

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

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Tissue	Cell type	Expression level	Type	Reliability
adrenal gland	glandular tissue	Negative	Staining	Uncertain
appendix	glandular tissue	Negative	Staining	Uncertain
appendix	lymphoid tissue	Negative	Staining	Uncertain
bone barrow	hematopoetic stem cell	Negative	Staining	Uncertain
bronchi	ciliated call with propulsive function of respiratory tract	Strong	Staining	Uncertain
cerebellum	granule cell	Moderate	Staining	Uncertain
cerebellum		Weak	Staining	Uncertain
cerebellum	purkinje cell	Moderate	Staining	Uncertain
cerebral cortex	glial cell of central nervous system	Moderate	Staining	Uncertain
cerebral cortex	neuron	Strong	Staining	Uncertain
cervix of uterus	glandular tissue	Weak	Staining	Uncertain
cervix of uterus	squamous epithelial cell	Negative	Staining	Uncertain
colon	glandular tissue	Moderate	Staining	Uncertain
duodenum	glandular tissue	Moderate	Staining	Uncertain
epididymis	glandular tissue	Negative	Staining	Uncertain

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