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Classification of Transcription Factors in Mammalia

About TFClass

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Superclass:

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,
Family:

, Subfamily:

, Genus:

,

1 Basic domains
2 Zinc-coordinating DNA-binding domains
3 Helix-turn-helix domains
4 Other all-alpha-helical DNA-binding domains
- 4.1 High-mobility group (HMG) domain factors
  - 4.1.1 SOX-related
    - 4.1.1.1 Group A
    - 4.1.1.2 Group B
    - 4.1.1.3 Group C
    - 4.1.1.4 Group D
    - 4.1.1.5 Group E
    - 4.1.1.6 Group F
      - 4.1.1.6.1 SOX7
      - 4.1.1.6.2 SOX17
      - 4.1.1.6.3 SOX18
    - 4.1.1.7 Group G
    - 4.1.1.8 Group H
    - 4.1.1.9 Further SOX-related
  - 4.1.2 TOX-related
  - 4.1.3 TCF7-related
  - 4.1.4 PBRM1-related
  - 4.1.5 WHSC1-related
  - 4.1.6 UBF-related
  - 4.1.7 TFAM
- 4.2 Heteromeric CCAAT-binding factors
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 18 LOGO plot of the DNA binding sequence

Species specific reports

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Bos taurus

Synonyms: cattle, domestic cow

Outlinks

Ensembl gene: ENSBTAG00000011662

Callithrix jacchus

Synonyms: white-tufted-ear marmoset, white ear-tufted marmoset

Outlinks

Ensembl gene: ENSCJAG00000022379

Canis lupus familiaris

Synonyms: dog, dogs

Outlinks

Ensembl: ENSCAFG00000029278

Cavia porcellus

Synonyms: domestic guinea pig, guinea pig

Outlinks

Ensembl: ENSCPOG00000024123

Dasypus novemcinctus

Synonyms: nine-banded armadillo

Outlinks

Ensembl gene: ENSDNOG00000036237

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000203883
Ensembl gene: ENSG00000203883
ProteinAtlas: ENSG00000203883 ( without antibody)
TRANSFAC: T04920
UniProt: P35713

Isoforms and DNA binding domain

Ictidomys tridecemlineatus

Synonyms: thirteen-lined ground squirrel

Outlinks

Ensembl gene: ENSSTOG00000028214
UniProt: NA

Macaca mulatta

Synonyms: Rhesus monkey, rhesus monkeys

Outlinks

Ensembl: ENSMMUG00000015560

Macropus eugenii

Synonyms: tammar wallaby

Outlinks

Ensembl: ENSMEUG00000016410

Monodelphis domestica

Synonyms: gray short-tailed opossum

Outlinks

Ensembl gene: ENSMODG00000017052
UniProt: NA

Mus musculus

Synonyms: house mouse, mouse

Outlinks

Ensembl gene: ENSMUSG00000046470
TRANSFAC: T01843
UniProt: P43680

Isoforms and DNA binding domain

Otolemur garnettii

Synonyms: small-eared galago

Outlinks

Ensembl gene: ENSOGAG00000032118

Pan troglodytes

Synonyms: chimpanzee

Outlinks

Ensembl gene: ENSPTRG00000030459

Procavia capensis

Synonyms: Cape rock hyrax, rock hyrax

Outlinks

Ensembl gene: ENSPCAG00000015663
UniProt: NA

Pteropus vampyrus

Synonyms: large flying fox

Outlinks

Ensembl gene: ENSPVAG00000014320
UniProt: NA

Rattus norvegicus

Synonyms: Norway rat, rats

Outlinks

Ensembl gene: ENSRNOG00000016248
UniProt: Q4V7E4

Isoforms and DNA binding domain

Sarcophilus harrisii

Synonyms: Tasmanian devil

Outlinks

Ensembl gene: ENSSHAG00000016686
UniProt: NA

Tursiops truncatus

Synonyms: bottlenose dolphin, bottle-nosed dolphin

Outlinks

Ensembl gene: ENSTTRG00000005878
UniProt: NA

Select species

Selected the species for which a species report should be shown.

Ailuropoda melanoleuca, giant panda
Bos taurus, cattle
Callithrix jacchus, white-tufted-ear marmoset
Canis lupus familiaris, dog
Cavia porcellus, domestic guinea pig
Choloepus hoffmanni, Hoffmann's two-fingered sloth
Dasypus novemcinctus, nine-banded armadillo
Dipodomys ordii, Ord's kangaroo rat
Echinops telfairi, small Madagascar hedgehog
Equus caballus, horse
Erinaceus europaeus, western European hedgehog
Felis catus, domestic cat
Gorilla gorilla gorilla, western lowland gorilla
Homo sapiens, human
Ictidomys tridecemlineatus, thirteen-lined ground squirrel
Loxodonta africana, African savanna elephant
Macaca mulatta, Rhesus monkey
Macropus eugenii, tammar wallaby
Microcebus murinus, gray mouse lemur
Monodelphis domestica, gray short-tailed opossum
Mus musculus, house mouse
Mustela putorius furo, domestic ferret
Myotis lucifugus, little brown bat
Nomascus leucogenys, northern white-cheeked gibbon
Ochotona princeps, American pika
Ornithorhynchus anatinus, platypus
Oryctolagus cuniculus, rabbit
Otolemur garnettii, small-eared galago
Ovis aries, sheep
Pan troglodytes, chimpanzee
Pongo abelii, Sumatran orangutan
Procavia capensis, Cape rock hyrax
Pteropus vampyrus, large flying fox
Rattus norvegicus, Norway rat
Sarcophilus harrisii, Tasmanian devil
Sorex araneus, European shrew
Sus scrofa, pig
Tarsius syrichta, Philippine tarsier
Tupaia belangeri, northern tree shrew
Tursiops truncatus, bottlenose dolphin
Vicugna pacos, alpaca

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology