Transcription factor classification

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Superclass:

, Class:

,
Family:

, Subfamily:

, Genus:

1 Basic domains
- 1.1 Basic leucine zipper factors (bZIP)
- 1.2 Basic helix-loop-helix factors (bHLH)
  - 1.2.1 E2A
  - 1.2.2 MyoD-ASC-related
    - 1.2.2.1 Myogenic TFs
      - 1.2.2.1.1 MyoD
      - 1.2.2.1.2 MYOG
      - 1.2.2.1.3 MYF5
      - 1.2.2.1.4 MYF6
    - 1.2.2.2 ASC
  - 1.2.3 Tal-related
  - 1.2.4 Hairy-related
  - 1.2.5 PAS
  - 1.2.6 bHLH-ZIP
  - 1.2.8 HLH only
- 1.3 Basic helix-span-helix factors (bHSH)
2 Zinc-coordinating DNA-binding domains
3 Helix-turn-helix domains
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 39

Species specific reports

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Ailuropoda melanoleuca

Synonyms: giant panda

Outlinks

Ensembl gene: ENSAMEG00000013193
UniProt: D2H509

Isoforms and DNA binding domain

Bos taurus

Synonyms: cattle, domestic cow

Outlinks

Ensembl gene: ENSBTAG00000026972
UniProt: P17667

Isoforms and DNA binding domain

Callithrix jacchus

Synonyms: white-tufted-ear marmoset, white ear-tufted marmoset

Outlinks

Ensembl gene: ENSCJAG00000019340

Canis lupus familiaris

Synonyms: dog, dogs

Outlinks

Ensembl: ENSCAFG00000005808

Cavia porcellus

Synonyms: domestic guinea pig, guinea pig

Outlinks

Ensembl gene: ENSCPOG00000007766

Choloepus hoffmanni

Synonyms: Hoffmann's two-fingered sloth, Hoffmann's two-toed sloth

Outlinks

Ensembl gene: ENSCHOG00000008319
UniProt: NA

Dasypus novemcinctus

Synonyms: nine-banded armadillo

Outlinks

Ensembl gene: ENSDNOG00000034747

Dipodomys ordii

Synonyms: Ord's kangaroo rat

Outlinks

Ensembl gene: ENSDORG00000015437
UniProt: NA

Echinops telfairi

Synonyms: small Madagascar hedgehog, lesser hedgehog tenrec

Outlinks

Ensembl gene: ENSETEG00000011255
UniProt: NA

Equus caballus

Synonyms: horse, equine

Outlinks

Ensembl gene: ENSECAG00000020047
UniProt: F7BTN2

Isoforms and DNA binding domain

Erinaceus europaeus

Synonyms: western European hedgehog, common hedgehog

Outlinks

Ensembl gene: ENSEEUG00000011612
UniProt: NA

Felis catus

Synonyms: domestic cat, cats

Outlinks

Ensembl gene: ENSFCAG00000015011

Gorilla gorilla gorilla

Synonyms: western lowland gorilla, lowland gorilla

Outlinks

Ensembl gene: ENSGGOG00000004366

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000111049
Ensembl gene: ENSG00000111049
ProteinAtlas: ENSG00000111049 ( with antibody)
TRANSFAC: T00521
UniProt: P13349

Protein expression pattern:Show tableIsoforms and DNA binding domain

Ictidomys tridecemlineatus

Synonyms: thirteen-lined ground squirrel

Outlinks

Ensembl gene: ENSSTOG00000015810
UniProt: NA

Loxodonta africana

Synonyms: African savanna elephant, African savannah elephant

Outlinks

Ensembl gene: ENSLAFG00000016473
UniProt: NA

Macaca mulatta

Synonyms: Rhesus monkey, rhesus monkeys

Outlinks

Ensembl gene: ENSMMUG00000011669
UniProt: F7HGT7

Isoforms and DNA binding domain

Macropus eugenii

Synonyms: tammar wallaby

Outlinks

Ensembl: ENSMEUG00000010628

Microcebus murinus

Synonyms: gray mouse lemur, grey mouse lemur

Outlinks

Ensembl: ENSMICG00000011211

Monodelphis domestica

Synonyms: gray short-tailed opossum

Outlinks

Ensembl gene: ENSMODG00000020478
UniProt: NA

Mus musculus

Synonyms: house mouse, mouse

Outlinks

Ensembl gene: ENSMUSG00000000435
TRANSFAC: T01534
UniProt: P24699

Isoforms and DNA binding domain

Mustela putorius furo

Synonyms: domestic ferret, ferret

Outlinks

Ensembl: ENSMPUG00000004935

Myotis lucifugus

Synonyms: little brown bat

Outlinks

Ensembl gene: ENSMLUG00000004943
UniProt: NA

Nomascus leucogenys

Synonyms: northern white-cheeked gibbon, White-cheeked Gibbon

Outlinks

Ensembl gene: ENSNLEG00000005207
UniProt: NA

Ochotona princeps

Synonyms: American pika, southern American pika

Outlinks

Ensembl gene: ENSOPRG00000009007
UniProt: NA

Ornithorhynchus anatinus

Synonyms: platypus, duckbill platypus

Outlinks

Ensembl gene: ENSOANG00000004853
UniProt: NA

Oryctolagus cuniculus

Synonyms: rabbit, rabbits

Outlinks

Ensembl gene: ENSOCUG00000025477
UniProt: G1U1L5

Isoforms and DNA binding domain

Otolemur garnettii

Synonyms: small-eared galago

Outlinks

Ensembl gene: ENSOGAG00000001039

Ovis aries

Synonyms: sheep, wild sheep

Outlinks

Ensembl gene: ENSOARG00000015159
UniProt: W5Q0M6

Isoforms and DNA binding domain

Pan troglodytes

Synonyms: chimpanzee

Outlinks

Ensembl gene: ENSPTRG00000005261

Pongo abelii

Synonyms: Sumatran orangutan, orang utan

Outlinks

Ensembl gene: ENSPPYG00000004800

Pteropus vampyrus

Synonyms: large flying fox

Outlinks

Ensembl gene: ENSPVAG00000003336
UniProt: NA

Rattus norvegicus

Synonyms: Norway rat, rats

Outlinks

Ensembl gene: ENSRNOG00000004768
UniProt: D3ZVU3

Isoforms and DNA binding domain

Sarcophilus harrisii

Synonyms: Tasmanian devil

Outlinks

Ensembl gene: ENSSHAG00000013391
UniProt: NA

Sus scrofa

Synonyms: pig, wild boar

Outlinks

Ensembl gene: ENSSSCG00000000937

Tarsius syrichta

Synonyms: Philippine tarsier

Outlinks

Ensembl: ENSTSYG00000003282

Tupaia belangeri

Synonyms: northern tree shrew, common tree shrew

Outlinks

Ensembl gene: ENSTBEG00000008363
UniProt: NA

Tursiops truncatus

Synonyms: bottlenose dolphin, bottle-nosed dolphin

Outlinks

Ensembl gene: ENSTTRG00000014691
UniProt: NA

Vicugna pacos

Synonyms: alpaca

Outlinks

Ensembl gene: ENSVPAG00000001927
UniProt: NA

Select species

Selected the species for which a species report should be shown.

Ailuropoda melanoleuca, giant panda
Bos taurus, cattle
Callithrix jacchus, white-tufted-ear marmoset
Canis lupus familiaris, dog
Cavia porcellus, domestic guinea pig
Choloepus hoffmanni, Hoffmann's two-fingered sloth
Dasypus novemcinctus, nine-banded armadillo
Dipodomys ordii, Ord's kangaroo rat
Echinops telfairi, small Madagascar hedgehog
Equus caballus, horse
Erinaceus europaeus, western European hedgehog
Felis catus, domestic cat
Gorilla gorilla gorilla, western lowland gorilla
Homo sapiens, human
Ictidomys tridecemlineatus, thirteen-lined ground squirrel
Loxodonta africana, African savanna elephant
Macaca mulatta, Rhesus monkey
Macropus eugenii, tammar wallaby
Microcebus murinus, gray mouse lemur
Monodelphis domestica, gray short-tailed opossum
Mus musculus, house mouse
Mustela putorius furo, domestic ferret
Myotis lucifugus, little brown bat
Nomascus leucogenys, northern white-cheeked gibbon
Ochotona princeps, American pika
Ornithorhynchus anatinus, platypus
Oryctolagus cuniculus, rabbit
Otolemur garnettii, small-eared galago
Ovis aries, sheep
Pan troglodytes, chimpanzee
Pongo abelii, Sumatran orangutan
Procavia capensis, Cape rock hyrax
Pteropus vampyrus, large flying fox
Rattus norvegicus, Norway rat
Sarcophilus harrisii, Tasmanian devil
Sorex araneus, European shrew
Sus scrofa, pig
Tarsius syrichta, Philippine tarsier
Tupaia belangeri, northern tree shrew
Tursiops truncatus, bottlenose dolphin
Vicugna pacos, alpaca

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

pp12345pp

Tissue	Cell type	Expression level	Type	Reliability
adrenal gland	glandular tissue	Strong	Staining	Uncertain
appendix	glandular tissue	Moderate	Staining	Uncertain
appendix	lymphoid tissue	Weak	Staining	Uncertain
bone barrow	hematopoetic stem cell	Strong	Staining	Uncertain
breast	glandular tissue	Moderate	Staining	Uncertain
bronchi	ciliated call with propulsive function of respiratory tract	Moderate	Staining	Uncertain
cerebellum	granule cell	Moderate	Staining	Uncertain
cerebellum		Weak	Staining	Uncertain
cerebellum	purkinje cell	Moderate	Staining	Uncertain
cerebral cortex	glial cell of central nervous system	Moderate	Staining	Uncertain
cerebral cortex	neuron	Moderate	Staining	Uncertain
cervix of uterus	glandular tissue	Moderate	Staining	Uncertain
cervix of uterus	squamous epithelial cell	Weak	Staining	Uncertain
colon	glandular tissue	Moderate	Staining	Uncertain
duodenum	glandular tissue	Moderate	Staining	Uncertain

pp12345pp

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Classification of Transcription Factors in Mammalia

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Species specific reports

Classification of Transcription Factors in Mammalia

About TFClass

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Species specific reports

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