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Classification of Transcription Factors in Mammalia

About TFClass

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Family:

, Subfamily:

, Genus:

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1 Basic domains
2 Zinc-coordinating DNA-binding domains
3 Helix-turn-helix domains
- 3.1 Homeo domain factors
  - 3.1.1 HOX
    - 3.1.1.1 HOX1
    - 3.1.1.2 HOX2
    - 3.1.1.3 HOX3
    - 3.1.1.4 HOX4
    - 3.1.1.5 HOX5
    - 3.1.1.6 HOX6-7
    - 3.1.1.7 HOX8
    - 3.1.1.8 HOX9-13
      - 3.1.1.8.1 HOXA9
      - 3.1.1.8.2 HOXB9
      - 3.1.1.8.3 HOXC9
      - 3.1.1.8.4 HOXD9
      - 3.1.1.8.5 HOXA10
      - 3.1.1.8.7 HOXC10
      - 3.1.1.8.8 HOXD10
      - 3.1.1.8.9 HOXA11
      - 3.1.1.8.10 HOXC11
      - 3.1.1.8.11 HOXD11
      - 3.1.1.8.12 HOXC12
      - 3.1.1.8.13 HOXD12
      - 3.1.1.8.14 HOXA13
      - 3.1.1.8.15 HOXB13
      - 3.1.1.8.16 HOXC13
      - 3.1.1.8.17 HOXD13
    - 3.1.1.9 CDX
    - 3.1.1.10 EVX
    - 3.1.1.11 GBX
    - 3.1.1.12 GSX
    - 3.1.1.13 MNX
    - 3.1.1.14 MEOX
    - 3.1.1.15 PDX
  - 3.1.2 NK
  - 3.1.3 Paired-related HD
  - 3.1.4 TALE-type HD
  - 3.1.5 HD-LIM
  - 3.1.6 HD-SINE
  - 3.1.7 HD-PROS
  - 3.1.8 HD-ZF
  - 3.1.9 HD-CUT
  - 3.1.10 POU
  - 3.1.11 PHTF
- 3.2 Paired box factors
- 3.3 Fork head / winged helix factors
- 3.4 Heat shock factors
- 3.5 Tryptophan cluster factors
- 3.6 TEA domain factors
- 3.7 ARID
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 33

Species specific reports

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Ailuropoda melanoleuca

Synonyms: giant panda

Outlinks

Ensembl gene: ENSAMEG00000000678

Bos taurus

Synonyms: cattle, domestic cow

Outlinks

Ensembl gene: ENSBTAG00000005606

Callithrix jacchus

Synonyms: white-tufted-ear marmoset, white ear-tufted marmoset

Outlinks

Ensembl gene: ENSCJAG00000018819
UniProt: F7I5W0

Isoforms and DNA binding domain

Canis lupus familiaris

Synonyms: dog, dogs

Outlinks

Ensembl: ENSCAFG00000032625

Choloepus hoffmanni

Synonyms: Hoffmann's two-fingered sloth, Hoffmann's two-toed sloth

Outlinks

Ensembl gene: ENSCHOG00000005906
UniProt: NA

Dasypus novemcinctus

Synonyms: nine-banded armadillo

Outlinks

Ensembl gene: ENSDNOG00000035825

Dipodomys ordii

Synonyms: Ord's kangaroo rat

Outlinks

Ensembl: ENSDORG00000006994

Equus caballus

Synonyms: horse, equine

Outlinks

Ensembl gene: ENSECAG00000000726

Erinaceus europaeus

Synonyms: western European hedgehog, common hedgehog

Outlinks

Ensembl gene: ENSEEUG00000002788
UniProt: NA

Felis catus

Synonyms: domestic cat, cats

Outlinks

Ensembl gene: ENSFCAG00000031037

Gorilla gorilla gorilla

Synonyms: western lowland gorilla, lowland gorilla

Outlinks

Ensembl gene: ENSGGOG00000006282

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000180806
Ensembl gene: ENSG00000180806
ProteinAtlas: ENSG00000180806 ( without antibody)
TRANSFAC: T03327
UniProt: P31274

Isoforms and DNA binding domain

Ictidomys tridecemlineatus

Synonyms: thirteen-lined ground squirrel

Outlinks

Ensembl gene: ENSSTOG00000012548
UniProt: NA

Loxodonta africana

Synonyms: African savanna elephant, African savannah elephant

Outlinks

Ensembl gene: ENSLAFG00000002366
UniProt: NA

Macaca mulatta

Synonyms: Rhesus monkey, rhesus monkeys

Outlinks

Ensembl: ENSMMUG00000000926

Macropus eugenii

Synonyms: tammar wallaby

Outlinks

Ensembl: ENSMEUG00000006605

Microcebus murinus

Synonyms: gray mouse lemur, grey mouse lemur

Outlinks

Ensembl gene: ENSMICG00000011714
UniProt: NA

Mus musculus

Synonyms: house mouse, mouse

Outlinks

Ensembl gene: ENSMUSG00000036139
TRANSFAC: T03349
UniProt: P09633

Isoforms and DNA binding domain

Mustela putorius furo

Synonyms: domestic ferret, ferret

Outlinks

Ensembl: ENSMPUG00000005862

Myotis lucifugus

Synonyms: little brown bat

Outlinks

Ensembl gene: ENSMLUG00000000483
UniProt: NA

Nomascus leucogenys

Synonyms: northern white-cheeked gibbon, White-cheeked Gibbon

Outlinks

Ensembl gene: ENSNLEG00000017678
UniProt: NA

Oryctolagus cuniculus

Synonyms: rabbit, rabbits

Outlinks

Ensembl gene: ENSOCUG00000001160

Otolemur garnettii

Synonyms: small-eared galago

Outlinks

Ensembl gene: ENSOGAG00000003616

Ovis aries

Synonyms: sheep, wild sheep

Outlinks

Ensembl gene: ENSOARG00000016319

Pan troglodytes

Synonyms: chimpanzee

Outlinks

Ensembl gene: ENSPTRG00000005029
UniProt: H2Q633

Isoforms and DNA binding domain

Pongo abelii

Synonyms: Sumatran orangutan, orang utan

Outlinks

Ensembl gene: ENSPPYG00000004592

Procavia capensis

Synonyms: Cape rock hyrax, rock hyrax

Outlinks

Ensembl gene: ENSPCAG00000010970
UniProt: NA

Pteropus vampyrus

Synonyms: large flying fox

Outlinks

Ensembl gene: ENSPVAG00000011039
UniProt: NA

Rattus norvegicus

Synonyms: Norway rat, rats

Outlinks

Ensembl gene: ENSRNOG00000016199
UniProt: D4A0V9

Isoforms and DNA binding domain

Sarcophilus harrisii

Synonyms: Tasmanian devil

Outlinks

Ensembl gene: ENSSHAG00000006807
UniProt: NA

Tupaia belangeri

Synonyms: northern tree shrew, common tree shrew

Outlinks

Ensembl gene: ENSTBEG00000015691
UniProt: NA

Tursiops truncatus

Synonyms: bottlenose dolphin, bottle-nosed dolphin

Outlinks

Ensembl gene: ENSTTRG00000010853
UniProt: NA

Vicugna pacos

Synonyms: alpaca

Outlinks

Ensembl gene: ENSVPAG00000003790
UniProt: NA

Select species

Selected the species for which a species report should be shown.

Ailuropoda melanoleuca, giant panda
Bos taurus, cattle
Callithrix jacchus, white-tufted-ear marmoset
Canis lupus familiaris, dog
Cavia porcellus, domestic guinea pig
Choloepus hoffmanni, Hoffmann's two-fingered sloth
Dasypus novemcinctus, nine-banded armadillo
Dipodomys ordii, Ord's kangaroo rat
Echinops telfairi, small Madagascar hedgehog
Equus caballus, horse
Erinaceus europaeus, western European hedgehog
Felis catus, domestic cat
Gorilla gorilla gorilla, western lowland gorilla
Homo sapiens, human
Ictidomys tridecemlineatus, thirteen-lined ground squirrel
Loxodonta africana, African savanna elephant
Macaca mulatta, Rhesus monkey
Macropus eugenii, tammar wallaby
Microcebus murinus, gray mouse lemur
Monodelphis domestica, gray short-tailed opossum
Mus musculus, house mouse
Mustela putorius furo, domestic ferret
Myotis lucifugus, little brown bat
Nomascus leucogenys, northern white-cheeked gibbon
Ochotona princeps, American pika
Ornithorhynchus anatinus, platypus
Oryctolagus cuniculus, rabbit
Otolemur garnettii, small-eared galago
Ovis aries, sheep
Pan troglodytes, chimpanzee
Pongo abelii, Sumatran orangutan
Procavia capensis, Cape rock hyrax
Pteropus vampyrus, large flying fox
Rattus norvegicus, Norway rat
Sarcophilus harrisii, Tasmanian devil
Sorex araneus, European shrew
Sus scrofa, pig
Tarsius syrichta, Philippine tarsier
Tupaia belangeri, northern tree shrew
Tursiops truncatus, bottlenose dolphin
Vicugna pacos, alpaca

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology