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Classification of Transcription Factors in Mammalia

About TFClass

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Family:

, Subfamily:

, Genus:

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1 Basic domains
2 Zinc-coordinating DNA-binding domains
3 Helix-turn-helix domains
- 3.1 Homeo domain factors
  - 3.1.1 HOX
    - 3.1.1.1 HOX1
    - 3.1.1.2 HOX2
    - 3.1.1.3 HOX3
    - 3.1.1.4 HOX4
    - 3.1.1.5 HOX5
    - 3.1.1.6 HOX6-7
    - 3.1.1.7 HOX8
      - 3.1.1.7.1 HOXB8
      - 3.1.1.7.2 HOXC8
      - 3.1.1.7.3 HOXD8
    - 3.1.1.8 HOX9-13
    - 3.1.1.9 CDX
    - 3.1.1.10 EVX
    - 3.1.1.11 GBX
    - 3.1.1.12 GSX
    - 3.1.1.13 MNX
    - 3.1.1.14 MEOX
    - 3.1.1.15 PDX
  - 3.1.2 NK
  - 3.1.3 Paired-related HD
  - 3.1.4 TALE-type HD
  - 3.1.5 HD-LIM
  - 3.1.6 HD-SINE
  - 3.1.7 HD-PROS
  - 3.1.8 HD-ZF
  - 3.1.9 HD-CUT
  - 3.1.10 POU
  - 3.1.11 PHTF
- 3.2 Paired box factors
- 3.3 Fork head / winged helix factors
- 3.4 Heat shock factors
- 3.5 Tryptophan cluster factors
- 3.6 TEA domain factors
- 3.7 ARID
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 30

Species specific reports

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Ailuropoda melanoleuca

Synonyms: giant panda

Outlinks

Ensembl gene: ENSAMEG00000000683
UniProt: D2HM45

Isoforms and DNA binding domain

Bos taurus

Synonyms: cattle, domestic cow

Outlinks

Ensembl gene: ENSBTAG00000012149

Callithrix jacchus

Synonyms: white-tufted-ear marmoset, white ear-tufted marmoset

Outlinks

Ensembl gene: ENSCJAG00000018828

Cavia porcellus

Synonyms: domestic guinea pig, guinea pig

Outlinks

Ensembl: ENSCPOG00000024489

Dasypus novemcinctus

Synonyms: nine-banded armadillo

Outlinks

Ensembl gene: ENSDNOG00000034735

Dipodomys ordii

Synonyms: Ord's kangaroo rat

Outlinks

Ensembl: ENSDORG00000006996

Equus caballus

Synonyms: horse, equine

Outlinks

Ensembl gene: ENSECAG00000000932

Erinaceus europaeus

Synonyms: western European hedgehog, common hedgehog

Outlinks

Ensembl gene: ENSEEUG00000008079
UniProt: NA

Felis catus

Synonyms: domestic cat, cats

Outlinks

Ensembl gene: ENSFCAG00000004769

Gorilla gorilla gorilla

Synonyms: western lowland gorilla, lowland gorilla

Outlinks

Ensembl gene: ENSGGOG00000006289

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000037965
Ensembl gene: ENSG00000037965
ProteinAtlas: ENSG00000037965 ( with antibody)
TRANSFAC: T03326
UniProt: P31273

Protein expression pattern:Show tableIsoforms and DNA binding domain

Ictidomys tridecemlineatus

Synonyms: thirteen-lined ground squirrel

Outlinks

Ensembl gene: ENSSTOG00000012551
UniProt: NA

Loxodonta africana

Synonyms: African savanna elephant, African savannah elephant

Outlinks

Ensembl gene: ENSLAFG00000018140
UniProt: NA

Macaca mulatta

Synonyms: Rhesus monkey, rhesus monkeys

Outlinks

Ensembl: ENSMMUG00000000928

Macropus eugenii

Synonyms: tammar wallaby

Outlinks

Ensembl: ENSMEUG00000006929

Microcebus murinus

Synonyms: gray mouse lemur, grey mouse lemur

Outlinks

Ensembl: ENSMICG00000011718

Mus musculus

Synonyms: house mouse, mouse

Outlinks

Ensembl gene: ENSMUSG00000001657
TRANSFAC: T01749
UniProt: P09025

Isoforms and DNA binding domain

Mustela putorius furo

Synonyms: domestic ferret, ferret

Outlinks

Ensembl: ENSMPUG00000005854

Myotis lucifugus

Synonyms: little brown bat

Outlinks

Ensembl gene: ENSMLUG00000003097
UniProt: NA

Nomascus leucogenys

Synonyms: northern white-cheeked gibbon, White-cheeked Gibbon

Outlinks

Ensembl gene: ENSNLEG00000017677
UniProt: NA

Ornithorhynchus anatinus

Synonyms: platypus, duckbill platypus

Outlinks

Ensembl gene: ENSOANG00000014218
UniProt: NA

Oryctolagus cuniculus

Synonyms: rabbit, rabbits

Outlinks

Ensembl gene: ENSOCUG00000004741

Otolemur garnettii

Synonyms: small-eared galago

Outlinks

Ensembl gene: ENSOGAG00000003619

Ovis aries

Synonyms: sheep, wild sheep

Outlinks

Ensembl gene: ENSOARG00000016306
UniProt: B5A7E0

Isoforms and DNA binding domain

Pan troglodytes

Synonyms: chimpanzee

Outlinks

Ensembl gene: ENSPTRG00000005030

Pongo abelii

Synonyms: Sumatran orangutan, orang utan

Outlinks

Ensembl gene: ENSPPYG00000004593

Pteropus vampyrus

Synonyms: large flying fox

Outlinks

Ensembl gene: ENSPVAG00000014725
UniProt: NA

Rattus norvegicus

Synonyms: Norway rat, rats

Outlinks

Ensembl gene: ENSRNOG00000028619

Sarcophilus harrisii

Synonyms: Tasmanian devil

Outlinks

Ensembl gene: ENSSHAG00000006951
UniProt: NA

Tursiops truncatus

Synonyms: bottlenose dolphin, bottle-nosed dolphin

Outlinks

Ensembl gene: ENSTTRG00000004538
UniProt: NA

Select species

Selected the species for which a species report should be shown.

Ailuropoda melanoleuca, giant panda
Bos taurus, cattle
Callithrix jacchus, white-tufted-ear marmoset
Canis lupus familiaris, dog
Cavia porcellus, domestic guinea pig
Choloepus hoffmanni, Hoffmann's two-fingered sloth
Dasypus novemcinctus, nine-banded armadillo
Dipodomys ordii, Ord's kangaroo rat
Echinops telfairi, small Madagascar hedgehog
Equus caballus, horse
Erinaceus europaeus, western European hedgehog
Felis catus, domestic cat
Gorilla gorilla gorilla, western lowland gorilla
Homo sapiens, human
Ictidomys tridecemlineatus, thirteen-lined ground squirrel
Loxodonta africana, African savanna elephant
Macaca mulatta, Rhesus monkey
Macropus eugenii, tammar wallaby
Microcebus murinus, gray mouse lemur
Monodelphis domestica, gray short-tailed opossum
Mus musculus, house mouse
Mustela putorius furo, domestic ferret
Myotis lucifugus, little brown bat
Nomascus leucogenys, northern white-cheeked gibbon
Ochotona princeps, American pika
Ornithorhynchus anatinus, platypus
Oryctolagus cuniculus, rabbit
Otolemur garnettii, small-eared galago
Ovis aries, sheep
Pan troglodytes, chimpanzee
Pongo abelii, Sumatran orangutan
Procavia capensis, Cape rock hyrax
Pteropus vampyrus, large flying fox
Rattus norvegicus, Norway rat
Sarcophilus harrisii, Tasmanian devil
Sorex araneus, European shrew
Sus scrofa, pig
Tarsius syrichta, Philippine tarsier
Tupaia belangeri, northern tree shrew
Tursiops truncatus, bottlenose dolphin
Vicugna pacos, alpaca

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

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Tissue	Cell type	Expression level	Type	Reliability
adrenal gland	glandular tissue	Moderate	Staining	Uncertain
appendix	glandular tissue	Weak	Staining	Uncertain
appendix	lymphoid tissue	Weak	Staining	Uncertain
bone barrow	hematopoetic stem cell	Moderate	Staining	Uncertain
breast	glandular tissue	Moderate	Staining	Uncertain
bronchi	ciliated call with propulsive function of respiratory tract	Moderate	Staining	Uncertain
cerebellum	granule cell	Negative	Staining	Uncertain
cerebellum		Strong	Staining	Uncertain
cerebellum	purkinje cell	Moderate	Staining	Uncertain
cerebral cortex	glial cell of central nervous system	Negative	Staining	Uncertain
cerebral cortex	neuron	Moderate	Staining	Uncertain
cervix of uterus	glandular tissue	Moderate	Staining	Uncertain
cervix of uterus	squamous epithelial cell	Negative	Staining	Uncertain
colon	glandular tissue	Moderate	Staining	Uncertain
duodenum	glandular tissue	Moderate	Staining	Uncertain

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