Transcription factor classification

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1 Basic domains
2 Zinc-coordinating DNA-binding domains
- 2.1 Nuclear receptors with C4 zinc fingers
- 2.2 Other C4 zinc finger-type factors
- 2.3 C2H2 zinc finger factors
  - 2.3.1 Three-zinc finger Krüppel-related
  - 2.3.2 Other factors with up to three adjacent zinc fingers
  - 2.3.3 More than 3 adjacent zinc fingers
    - 2.3.3.1 GLI-lile
    - 2.3.3.2 Snail-like
    - 2.3.3.3 ZFP91-like
    - 2.3.3.4 ZNF280-like
    - 2.3.3.5 ZSCAN5-like
    - 2.3.3.6 ZNF75-like
    - 2.3.3.7 ZNF705
    - 2.3.3.8 ZBTB7
    - 2.3.3.9 YY1-like
      - 2.3.3.9.1 YY1 (YY12)
      - 2.3.3.9.2 YY2
      - 2.3.3.9.3 ZFP42
    - 2.3.3.10 ZNF24-like
    - 2.3.3.11 ZBTB6-like
    - 2.3.3.12 PRDM1-like
    - 2.3.3.13 ZNF148-like
    - 2.3.3.14 ZBTB20-like
    - 2.3.3.15 ZNF524-like
    - 2.3.3.16 ZNF238-like
    - 2.3.3.17 OVOL
    - 2.3.3.18 ZNF56-like
    - 2.3.3.19 ZNF500-like
    - 2.3.3.20 FEZF
    - 2.3.3.21 GFI1
    - 2.3.3.22 BCL6
    - 2.3.3.23 ZNF212-like
    - 2.3.3.24 MTF1-like
    - 2.3.3.25 PLAG
    - 2.3.3.26 ZKSCAN3-like
    - 2.3.3.27 ZNF525-like
    - 2.3.3.28 ZNF76-like
    - 2.3.3.29 ZNF652-like
    - 2.3.3.30 ZNF350-like
    - 2.3.3.31 ZNF642-like
    - 2.3.3.32 ZNF679-like
    - 2.3.3.33 ZNF763-like
    - 2.3.3.34 ZNF3-like
    - 2.3.3.35 ZNF620-like
    - 2.3.3.36 ZNF324
    - 2.3.3.37 ZNF362-like
    - 2.3.3.38 ZNF282-like
    - 2.3.3.39 ZNF764-like
    - 2.3.3.40 ZNF177-like
    - 2.3.3.41 ZNF32-like
    - 2.3.3.42 ZNF773-like
    - 2.3.3.43 ZNF558-like
    - 2.3.3.44 ZNF302-like
    - 2.3.3.45 ZNF562-like
    - 2.3.3.46 ZXD
    - 2.3.3.47 ZNF222-like
    - 2.3.3.48 ZNF736-like
    - 2.3.3.49 ZNF286
    - 2.3.3.50 CTCF-like
    - 2.3.3.51 ZNF366-like
    - 2.3.3.52 ZNF322-like
    - 2.3.3.53 ZNF548-like
    - 2.3.3.54 ZNF460-like
    - 2.3.3.55 ZNF146-like
    - 2.3.3.56 ZNF214-like
    - 2.3.3.57 ZNF479-like
    - 2.3.3.58 ZNF180-like
    - 2.3.3.59 ZNF100-like
    - 2.3.3.60 ZNF98-like
    - 2.3.3.61 ZNF343-like
    - 2.3.3.62 ZFP2-like
    - 2.3.3.63 ZFP30-like
    - 2.3.3.64 ZNF354A-like
    - 2.3.3.65 ZFX-ZFY
    - 2.3.3.66 ZNF689-like
    - 2.3.3.67 ZNF283-like
    - 2.3.3.68 ZNF81-like
    - 2.3.3.69 ZNF25-like
    - 2.3.3.70 ZNF26-like
    - 2.3.3.71 ZNF300-like
    - 2.3.3.72 ZNF813-like
    - 2.3.3.73 ZNF816A-like
    - 2.3.3.74 ZNF442-like
    - 2.3.3.75 ZNF432-like
    - 2.3.3.76 ZNF665-like
    - 2.3.3.77 ZNF595-like
    - 2.3.3.78 ZNF14-like
    - 2.3.3.79 ZNF841-like
    - 2.3.3.80 ZNF99-like
    - 2.3.3.0.1 ZFP161
    - 2.3.3.0.10 ZNF781
    - 2.3.3.0.11 ZNF114
    - 2.3.3.0.12 ZNF589
    - 2.3.3.0.13 ZNF22
    - 2.3.3.0.14 ZNF713
    - 2.3.3.0.15 ZSCAN16
    - 2.3.3.0.20 ZNF18
    - 2.3.3.0.21 WT1
    - 2.3.3.0.23 PRDM6
    - 2.3.3.0.24 ZNF444
    - 2.3.3.0.25 ZNF641
    - 2.3.3.0.26 ZNF746
    - 2.3.3.0.27 ZIM2
    - 2.3.3.0.31 ZNF655
    - 2.3.3.0.32 ZNF165
    - 2.3.3.0.34 ZNF131
    - 2.3.3.0.35 PRDM14
    - 2.3.3.0.37 ZNF575
    - 2.3.3.0.38 ZBTB49
    - 2.3.3.0.39 ZNF691
    - 2.3.3.0.43 ZSCAN30
    - 2.3.3.0.45 ZNF80
    - 2.3.3.0.46 ZNF514
    - 2.3.3.0.47 ZSCAN21
    - 2.3.3.0.54 MYNN
    - 2.3.3.0.55 ZBTB24
    - 2.3.3.0.57 ZFP92
    - 2.3.3.0.58 ZNF205
    - 2.3.3.0.59 ZNF837
    - 2.3.3.0.67 ZNF584
    - 2.3.3.0.68 ZNF684
    - 2.3.3.0.69 ZNF187
    - 2.3.3.0.70 ZSCAN22
    - 2.3.3.0.71 ZNF550
    - 2.3.3.0.78 ZNF696
    - 2.3.3.0.79 ZNF263
    - 2.3.3.0.80 ZNF556
    - 2.3.3.0.81 ZNF192
    - 2.3.3.0.82 ZNF391
    - 2.3.3.0.83 ZNF239
    - 2.3.3.0.91 ZNF660
    - 2.3.3.0.92 GZF1
    - 2.3.3.0.93 ZNF408
    - 2.3.3.0.94 ZNF648
    - 2.3.3.0.95 ZNF768
    - 2.3.3.0.100 ZNF35
    - 2.3.3.0.101 ZNF483
    - 2.3.3.0.102 ZBTB48
    - 2.3.3.0.103 ZNF275
    - 2.3.3.0.104 ZIM3
    - 2.3.3.0.106 ZNF596
    - 2.3.3.0.111 ZNF718
    - 2.3.3.0.112 ZNF121
    - 2.3.3.0.113 ZNF485
    - 2.3.3.0.114 ZNF354C
    - 2.3.3.0.115 ZNF586
    - 2.3.3.0.118 ZNF10
    - 2.3.3.0.119 ZNF19
    - 2.3.3.0.123 ZBTB40
    - 2.3.3.0.124 ZBTB11
    - 2.3.3.0.125 ZNF454
    - 2.3.3.0.126 ZNF154
    - 2.3.3.0.127 ZNF416
    - 2.3.3.0.130 ZNF34
    - 2.3.3.0.136 ZNF320
    - 2.3.3.0.142 ZNF331
    - 2.3.3.0.148 ZNF329
    - 2.3.3.0.149 ZFP90
    - 2.3.3.0.150 ZNF317
    - 2.3.3.0.159 ZNF167
    - 2.3.3.0.160 ZNF250
    - 2.3.3.0.161 ZNF623
    - 2.3.3.0.162 ZFP3
    - 2.3.3.0.165 ZNF266
    - 2.3.3.0.166 ZNF311
    - 2.3.3.0.173 ZNF880
    - 2.3.3.0.174 ZNF287
    - 2.3.3.0.180 ZNF549
    - 2.3.3.0.183 ZNF676
    - 2.3.3.0.186 ZNF267
    - 2.3.3.0.191 ZNF471
    - 2.3.3.0.192 ZFP28
    - 2.3.3.0.193 ZNF182
    - 2.3.3.0.195 PRDM5
    - 2.3.3.0.196 RBAK
    - 2.3.3.0.197 ZNF189
    - 2.3.3.0.202 ZNF135
    - 2.3.3.0.210 ZNF23
    - 2.3.3.0.215 ZNF569
    - 2.3.3.0.216 ZNF84
    - 2.3.3.0.220 ZNF184
    - 2.3.3.0.221 ZNF441
    - 2.3.3.0.224 ZNF433
    - 2.3.3.0.225 ZNF337
    - 2.3.3.0.226 ZNF726
    - 2.3.3.0.227 ZNF624
    - 2.3.3.0.228 ZNF197
    - 2.3.3.0.232 ZNF594
    - 2.3.3.0.233 ZNF107
    - 2.3.3.0.234 ZNF208
    - 2.3.3.0 unclassified
    - 2.3.3.0.3 ZNF496
    - 2.3.3.0.6 ZNF274
    - 2.3.3.0.7 ZNF200
    - 2.3.3.0.9 OSR2
    - 2.3.3.0.16 ZNF793
    - 2.3.3.0.17 ZFP41
    - 2.3.3.0.18 ZNF215
    - 2.3.3.0.28 ZBTB44
    - 2.3.3.0.30 ZNF576
    - 2.3.3.0.40 ZNF394
    - 2.3.3.0.41 ZNF449
    - 2.3.3.0.42 ZNF498 (ZSCAN25)
    - 2.3.3.0.51 ZNF707
    - 2.3.3.0.60 ZNF202
    - 2.3.3.0.61 ZNF789
    - 2.3.3.0.62 ZNF662
    - 2.3.3.0.63 ZNF554
    - 2.3.3.0.64 ZNF506
    - 2.3.3.0.72 ZFP1
    - 2.3.3.0.74 ZBTB16
    - 2.3.3.0.75 GTF3A
    - 2.3.3.0.76 ZFP64
    - 2.3.3.0.77 ZNF358
    - 2.3.3.0.84 ZNF664
    - 2.3.3.0.87 ZNF501
    - 2.3.3.0.89 ZNF610
    - 2.3.3.0.96 ZNF517
    - 2.3.3.0.97 ZNF547
    - 2.3.3.0.98 ZNF766
    - 2.3.3.0.99 ZNF677
    - 2.3.3.0.109 ZNF682
    - 2.3.3.0.110 ZNF141
    - 2.3.3.0.120 ZSCAN12
    - 2.3.3.0.121 ZNF70
    - 2.3.3.0.122 ZNF79
    - 2.3.3.0.132 ZNF74
    - 2.3.3.0.133 ZNF415
    - 2.3.3.0.134 ZNF480
    - 2.3.3.0.143 ZNF461
    - 2.3.3.0.145 ZNF529
    - 2.3.3.0.146 ZNF565
    - 2.3.3.0.152 MZF1
    - 2.3.3.0.153 ZNF530
    - 2.3.3.0.156 ZNF695
    - 2.3.3.0.157 ZNF879
    - 2.3.3.0.158 ZNF790
    - 2.3.3.0.167 ZNF551
    - 2.3.3.0.168 ZNF497
    - 2.3.3.0.169 ZSCAN10
    - 2.3.3.0.175 ZNF502
    - 2.3.3.0.176 ZNF835
    - 2.3.3.0.177 ZNF560
    - 2.3.3.0.179 ZNF667
    - 2.3.3.0.188 ZNF83
    - 2.3.3.0.189 ZNF528
    - 2.3.3.0.190 ZNF7
    - 2.3.3.0.204 ZNF16
    - 2.3.3.0.205 ZNF17
    - 2.3.3.0.207 ZNF534
    - 2.3.3.0.209 ZNF791
    - 2.3.3.0.217 ZNF749
    - 2.3.3.0.218 ZNF425
    - 2.3.3.0.229 ZNF493
    - 2.3.3.0.230 ZNF43
    - 2.3.3.0.231 ZFP62
    - 2.3.3.0.235 ZNF91
  - 2.3.4 Factors with multiple dispersed zinc fingers
  - 2.3.5 BED zinc finger factors
- 2.5 DM-type intertwined zinc finger factors
- 2.6 CXXC zinc finger factors
- 2.7 C2HC
- 2.8 C3H zinc finger factors
- 2.9 C2CH THAP-type zinc finger factors
3 Helix-turn-helix domains
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 15 LOGO plot of the DNA binding sequence

Species specific reports

Jump to human, mouse or rat
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Ailuropoda melanoleuca

Synonyms: giant panda

Outlinks

Ensembl gene: ENSAMEG00000016465

Choloepus hoffmanni

Synonyms: Hoffmann's two-fingered sloth, Hoffmann's two-toed sloth

Outlinks

Ensembl gene: ENSCHOG00000010920
UniProt: NA

Dipodomys ordii

Synonyms: Ord's kangaroo rat

Outlinks

Ensembl gene: ENSDORG00000011068
UniProt: NA

Equus caballus

Synonyms: horse, equine

Outlinks

Ensembl gene: ENSECAG00000014804

Erinaceus europaeus

Synonyms: western European hedgehog, common hedgehog

Outlinks

Ensembl gene: ENSEEUG00000010704
UniProt: NA

Gorilla gorilla gorilla

Synonyms: western lowland gorilla, lowland gorilla

Outlinks

Ensembl gene: ENSGGOG00000034967

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000230797
Ensembl gene: ENSG00000230797
ProteinAtlas: ENSG00000230797 ( with antibody)
TRANSFAC: T21350
UniProt: O15391

Protein expression pattern:Show tableIsoforms and DNA binding domain

Macaca mulatta

Synonyms: Rhesus monkey, rhesus monkeys

Outlinks

Ensembl gene: ENSMMUG00000022467

Microcebus murinus

Synonyms: gray mouse lemur, grey mouse lemur

Outlinks

Ensembl: ENSMICG00000008932

Monodelphis domestica

Synonyms: gray short-tailed opossum

Outlinks

Ensembl gene: ENSMODG00000028019
UniProt: NA

Mus musculus

Synonyms: house mouse, mouse

Outlinks

Ensembl gene: ENSMUSG00000091736
TRANSFAC: T17589
UniProt: Q3TTC2

Isoforms and DNA binding domain

Myotis lucifugus

Synonyms: little brown bat

Outlinks

Ensembl gene: ENSMLUG00000025014
UniProt: NA

Sarcophilus harrisii

Synonyms: Tasmanian devil

Outlinks

Ensembl gene: ENSSHAG00000010068
UniProt: NA

Sus scrofa

Synonyms: pig, wild boar

Outlinks

Ensembl: ENSSSCG00000030865

Tupaia belangeri

Synonyms: northern tree shrew, common tree shrew

Outlinks

Ensembl gene: ENSTBEG00000011527
UniProt: NA

Select species

Selected the species for which a species report should be shown.

Ailuropoda melanoleuca, giant panda
Bos taurus, cattle
Callithrix jacchus, white-tufted-ear marmoset
Canis lupus familiaris, dog
Cavia porcellus, domestic guinea pig
Choloepus hoffmanni, Hoffmann's two-fingered sloth
Dasypus novemcinctus, nine-banded armadillo
Dipodomys ordii, Ord's kangaroo rat
Echinops telfairi, small Madagascar hedgehog
Equus caballus, horse
Erinaceus europaeus, western European hedgehog
Felis catus, domestic cat
Gorilla gorilla gorilla, western lowland gorilla
Homo sapiens, human
Ictidomys tridecemlineatus, thirteen-lined ground squirrel
Loxodonta africana, African savanna elephant
Macaca mulatta, Rhesus monkey
Macropus eugenii, tammar wallaby
Microcebus murinus, gray mouse lemur
Monodelphis domestica, gray short-tailed opossum
Mus musculus, house mouse
Mustela putorius furo, domestic ferret
Myotis lucifugus, little brown bat
Nomascus leucogenys, northern white-cheeked gibbon
Ochotona princeps, American pika
Ornithorhynchus anatinus, platypus
Oryctolagus cuniculus, rabbit
Otolemur garnettii, small-eared galago
Ovis aries, sheep
Pan troglodytes, chimpanzee
Pongo abelii, Sumatran orangutan
Procavia capensis, Cape rock hyrax
Pteropus vampyrus, large flying fox
Rattus norvegicus, Norway rat
Sarcophilus harrisii, Tasmanian devil
Sorex araneus, European shrew
Sus scrofa, pig
Tarsius syrichta, Philippine tarsier
Tupaia belangeri, northern tree shrew
Tursiops truncatus, bottlenose dolphin
Vicugna pacos, alpaca

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

pp12345pp

Tissue	Cell type	Expression level	Type	Reliability
adrenal gland	glandular tissue	Weak	Staining	Supportive
appendix	glandular tissue	Strong	Staining	Supportive
appendix	lymphoid tissue	Strong	Staining	Supportive
bone barrow	hematopoetic stem cell	Negative	Staining	Supportive
breast	glandular tissue	Moderate	Staining	Supportive
bronchi	ciliated call with propulsive function of respiratory tract	Moderate	Staining	Supportive
cerebellum	granule cell	Negative	Staining	Supportive
cerebellum		Negative	Staining	Supportive
cerebellum	purkinje cell	Negative	Staining	Supportive
cerebral cortex	glial cell of central nervous system	Negative	Staining	Supportive
cerebral cortex	neuron	Negative	Staining	Supportive
cervix of uterus	glandular tissue	Moderate	Staining	Supportive
cervix of uterus	squamous epithelial cell	Moderate	Staining	Supportive
colon	glandular tissue	Moderate	Staining	Supportive
duodenum	glandular tissue	Moderate	Staining	Supportive

pp12345pp

Classification of Transcription Factors in Mammalia

About TFClass

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Species specific reports

Classification of Transcription Factors in Mammalia

About TFClass

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Species specific reports

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