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Classification of Transcription Factors in Mammalia

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  • 4 Other all-alpha-helical DNA-binding domains
    • 4.1 High-mobility group (HMG) domain factors

Consensus binding sequenceACAAPredicted binding sites For: human, mouse, cow, dogSpecies within this Family: 41 Genera within this Family: 23 LOGO plot of the DNA binding domain
FASTA file of the LogoPlot
DNA binding domain Whole protein
Phylogenetic tree
These trees (or cladograms, since distances were ignored) were generated with a local installation of PhyML 3.0 (Guindon et al., Systematic Biology, 59(3):307-21, 2010.), by webPRANK at EBI (, or by the web version of PhyML 3.0 ( The resulting trees were visualized with iTOL v3 (
  • and iTOL
  • webPRANK and iTOL
    Phylogenetic tree Mammalia
    (slim selection)
    To generate these trees, only the TFs were taken from a selected group of mammalian species. As standard, the corresponding human, cow, mouse and Monodelphis TFs were taken if available; occasionally, either species was to replaced or had to be omitted without replacement.
      • and iTOL
      Select species

      Selected the species for which a species report should be shown.

      Expression table
      The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

      The selected tree node is not linked to a gene, no expression data is available.