About Tryptophan cluster factorsTRANSFAC
® class description C0022: The tryptophan clusters comprise several tryptophan residues with a spacing of 12-21 amino acid residues; the subclass of myb-type DNA-binding domains typically exhibit a spacing of 19-21 amino acid residues. All IRF family members, except IRF-1 and IRF-2, contain conserved IAD, IRF association domain that is responsible for protein-protein interactions with other IRF family members or with Ets factor PU.1 and/or bHLH factor E47. IRF-1 and IRF-2 contain IAD2 that is conserved between them and, like IAD, involved in protein-protein interactions. (PMID 10586038)
More informationSpecies within this Class: 41
Genera within this Class: 68
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DNA binding domain |
Whole protein |
FASTA |
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