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Classification of Transcription Factors in Mammalia

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Superclass: , Class: ,
Family: , Subfamily: , Genus: ,
  • 3 Helix-turn-helix domains
About Tryptophan cluster factors
TRANSFAC® class description C0022: The tryptophan clusters comprise several tryptophan residues with a spacing of 12-21 amino acid residues; the subclass of myb-type DNA-binding domains typically exhibit a spacing of 19-21 amino acid residues. All IRF family members, except IRF-1 and IRF-2, contain conserved IAD, IRF association domain that is responsible for protein-protein interactions with other IRF family members or with Ets factor PU.1 and/or bHLH factor E47. IRF-1 and IRF-2 contain IAD2 that is conserved between them and, like IAD, involved in protein-protein interactions. (PMID 10586038) More informationSpecies within this Class: 41 Genera within this Class: 68
DNA binding domain Whole protein
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Expression table
The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

The selected tree node is not linked to a gene, no expression data is available.