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Classification of Transcription Factors in Mammalia

About TFClass

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Superclass: , Class: ,
Family: , Subfamily: , Genus: ,
  • 3 Helix-turn-helix domains
About Fork head / winged helix factors
TRANSFAC® class description C0023: Identified by homology between HNF-3A and fkh. The domain comprises approx. 110 AA. Analysis of the crystal structure has revealed a compact structure of three alpha-helices, the third alpha-helix being exposed towards the major groove of the DNA. The domain also exerts minor groove contacts. Upon binding to DNA, it induces a bend of 13 degree. More informationSpecies within this Class: 41 Genera within this Class: 67 LOGO plot of the DNA binding domain
FASTA file of the LogoPlot
DNA binding domain Whole protein
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Expression table
The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

The selected tree node is not linked to a gene, no expression data is available.