About C3H zinc finger factorsClass description: These factors comprise a putative zinc finger motif with the signature C------C-----C---H. DNA-binding has been proven only for three proteins of this class, ZC3H8 (2.8.1.0.1), of which closely related proteins have been included for similarity, ZGPAT (2.8.2.0.1), with no close relatives found, and RC3H2 (2.8.4.0.1). Most, if not all, other proteins of this class appear to be RNA-binders and be involved more likely in splicing rather than transcriptional regulation.
More informationSpecies within this Class: 37
Genera within this Class: 6
LOGO plot of the DNA binding domain
FASTA file of the LogoPlot
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DNA binding domain |
Whole protein |
| FASTA |
FASTA file |
FASTA file |
Phylogenetic tree
Mammalia
These trees (or cladograms, since distances were ignored) were generated with a local installation of PhyML 3.0 (Guindon et al., Systematic Biology, 59(3):307-21, 2010.), by webPRANK at EBI (http://www.ebi.ac.uk/goldman-srv/webprank/), or by the web version of PhyML 3.0 (http://phylogeny.lirmm.fr). The resulting trees were visualized with iTOL v3 (http://itol.embl.de/).
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Phylogenetic tree Mammalia
(slim selection)
To generate these trees, only the TFs were taken from a selected group of mammalian species. As standard, the corresponding human, cow, mouse and Monodelphis TFs were taken if available; occasionally, either species was to replaced or had to be omitted without replacement.
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