Transcription factor classification

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1 Basic domains
2 Zinc-coordinating DNA-binding domains
- 2.1 Nuclear receptors with C4 zinc fingers
- 2.2 Other C4 zinc finger-type factors
- 2.3 C2H2 zinc finger factors
  - 2.3.1 Three-zinc finger Krüppel-related
  - 2.3.2 Other factors with up to three adjacent zinc fingers
  - 2.3.3 More than 3 adjacent zinc fingers
  - 2.3.4 Factors with multiple dispersed zinc fingers
    - 2.3.4.1 ZNF417-like
    - 2.3.4.2 ZNF219-like
    - 2.3.4.3 SAL-like
    - 2.3.4.4 Ikaros
    - 2.3.4.5 HIV EP
    - 2.3.4.6 ZBTB1-like
    - 2.3.4.7 RLF-like
    - 2.3.4.8 MAZ-like
    - 2.3.4.9 ZNF532-like
    - 2.3.4.10 ZNF512
    - 2.3.4.11 ZNF658
    - 2.3.4.12 ZNF423-like
    - 2.3.4.13 ZNF639-like
    - 2.3.4.14 EVI1-like
    - 2.3.4.15 BCL11
    - 2.3.4.16 Insulinoma-associated proteins
    - 2.3.4.17 HIC
    - 2.3.4.18 ZNF518
    - 2.3.4.19 Basonuclin
    - 2.3.4.20 TRERF1-like
    - 2.3.4.21 HINFP-like
    - 2.3.4.22 ZNF526-like
    - 2.3.4.23 ZNF319-like
    - 2.3.4.24 ZNF134-like
      - 2.3.4.24.1 ZNF134
      - 2.3.4.24.2 ZNF671
      - 2.3.4.24.3 ZNF772
      - 2.3.4.24.4 ZNF792
    - 2.3.4.25 ZNF37A-like
    - 2.3.4.0.1 CASZ1
    - 2.3.4.0.2 ZNF335
    - 2.3.4.0.4 WIZ
    - 2.3.4.0.5 ZNF469
    - 2.3.4.0.6 ZFPM1
    - 2.3.4.0.7 ZBTB4
    - 2.3.4.0.9 ZBTB39
    - 2.3.4.0.10 ZNF295
    - 2.3.4.0.12 PRDM13
    - 2.3.4.0.13 ZNF646
    - 2.3.4.0.14 ZNF579
    - 2.3.4.0.16 PRDM2
    - 2.3.4.0.17 ZNF800
    - 2.3.4.0.18 ZNF618
    - 2.3.4.0.21 ZNF451
    - 2.3.4.0.22 ZNF438
    - 2.3.4.0.24 ZNF507
    - 2.3.4.0.25 ZNF236
    - 2.3.4.0.26 ZNF770
    - 2.3.4.0.28 ZFP57
    - 2.3.4.0.30 ZNF597
    - 2.3.4.0.32 PRDM15
    - 2.3.4.0.33 ZBTB41
    - 2.3.4.0.34 PRDM10
    - 2.3.4.0.36 ZNF513
    - 2.3.4.0.37 ZNF142
    - 2.3.4.0.38 FIZ1
    - 2.3.4.0.40 ZNF784
    - 2.3.4.0.41 ZNF697
    - 2.3.4.0.42 ZKSCAN5
    - 2.3.4.0.44 ZNF775
    - 2.3.4.0.45 ZNF467
    - 2.3.4.0.46 ZNF787
    - 2.3.4.0.48 ZNF48
    - 2.3.4.0.49 ZNF629
    - 2.3.4.0.50 ZNF668
    - 2.3.4.0.51 ZNF101
    - 2.3.4.0.52 ZNF251
    - 2.3.4.0.53 ZNF445
    - 2.3.4.0.56 ZSCAN20
    - 2.3.4.0.57 ZNF674
    - 2.3.4.0.60 ZNF788
    - 2.3.4.0.63 ZNF778
    - 2.3.4.0.68 ZNF519
    - 2.3.4.0.69 ZNF304
    - 2.3.4.0.70 ZNF132
    - 2.3.4.0.72 ZBTB17
    - 2.3.4.0.73 ZNF407
    - 2.3.4.0.74 E4F1
    - 2.3.4.0 unclassified
    - 2.3.4.0.3 PRDM8
    - 2.3.4.0.8 ZBTB38
    - 2.3.4.0.15 RREB1
    - 2.3.4.0.19 ZNF277
    - 2.3.4.0.23 PEG3
    - 2.3.4.0.27 REST
    - 2.3.4.0.31 PRDM4
    - 2.3.4.0.35 ZNF341
    - 2.3.4.0.39 ZNF628
    - 2.3.4.0.43 ZNF316
    - 2.3.4.0.59 ZNF195
    - 2.3.4.0.67 ZNF606
    - 2.3.4.0.71 PRDM9
    - 2.3.4.0.75 ZNF462
    - 2.3.4.0.76 ZNF644
  - 2.3.5 BED zinc finger factors
- 2.5 DM-type intertwined zinc finger factors
- 2.6 CXXC zinc finger factors
- 2.7 C2HC
- 2.8 C3H zinc finger factors
- 2.9 C2CH THAP-type zinc finger factors
3 Helix-turn-helix domains
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 14

Species specific reports

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Ailuropoda melanoleuca

Synonyms: giant panda

Outlinks

Ensembl gene: ENSAMEG00000001439

Dasypus novemcinctus

Synonyms: nine-banded armadillo

Outlinks

Ensembl gene: ENSDNOG00000000486

Equus caballus

Synonyms: horse, equine

Outlinks

Ensembl gene: ENSECAG00000019272

Gorilla gorilla gorilla

Synonyms: western lowland gorilla, lowland gorilla

Outlinks

Ensembl gene: ENSGGOG00000013454

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000083814
Ensembl gene: ENSG00000083814
ProteinAtlas: ENSG00000083814 ( with antibody)
TRANSFAC: T20963
UniProt: Q8TAW3

Protein expression pattern:Show tableIsoforms and DNA binding domain

Macaca mulatta

Synonyms: Rhesus monkey, rhesus monkeys

Outlinks

Ensembl gene: ENSMMUG00000023357
UniProt: F7HNW0

Isoforms and DNA binding domain

Microcebus murinus

Synonyms: gray mouse lemur, grey mouse lemur

Outlinks

Ensembl gene: ENSMICG00000006591
UniProt: NA

Mustela putorius furo

Synonyms: domestic ferret, ferret

Outlinks

Ensembl: ENSMPUG00000008431

Nomascus leucogenys

Synonyms: northern white-cheeked gibbon, White-cheeked Gibbon

Outlinks

Ensembl gene: ENSNLEG00000010999
UniProt: NA

Otolemur garnettii

Synonyms: small-eared galago

Outlinks

Ensembl gene: ENSOGAG00000028005

Pan troglodytes

Synonyms: chimpanzee

Outlinks

Ensembl gene: ENSPTRG00000011569

Pongo abelii

Synonyms: Sumatran orangutan, orang utan

Outlinks

Ensembl gene: ENSPPYG00000010482

Sus scrofa

Synonyms: pig, wild boar

Outlinks

Ensembl gene: ENSSSCG00000003990

Tursiops truncatus

Synonyms: bottlenose dolphin, bottle-nosed dolphin

Outlinks

Ensembl gene: ENSTTRG00000016323
UniProt: NA

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Ailuropoda melanoleuca, giant panda
Bos taurus, cattle
Callithrix jacchus, white-tufted-ear marmoset
Canis lupus familiaris, dog
Cavia porcellus, domestic guinea pig
Choloepus hoffmanni, Hoffmann's two-fingered sloth
Dasypus novemcinctus, nine-banded armadillo
Dipodomys ordii, Ord's kangaroo rat
Echinops telfairi, small Madagascar hedgehog
Equus caballus, horse
Erinaceus europaeus, western European hedgehog
Felis catus, domestic cat
Gorilla gorilla gorilla, western lowland gorilla
Homo sapiens, human
Ictidomys tridecemlineatus, thirteen-lined ground squirrel
Loxodonta africana, African savanna elephant
Macaca mulatta, Rhesus monkey
Macropus eugenii, tammar wallaby
Microcebus murinus, gray mouse lemur
Monodelphis domestica, gray short-tailed opossum
Mus musculus, house mouse
Mustela putorius furo, domestic ferret
Myotis lucifugus, little brown bat
Nomascus leucogenys, northern white-cheeked gibbon
Ochotona princeps, American pika
Ornithorhynchus anatinus, platypus
Oryctolagus cuniculus, rabbit
Otolemur garnettii, small-eared galago
Ovis aries, sheep
Pan troglodytes, chimpanzee
Pongo abelii, Sumatran orangutan
Procavia capensis, Cape rock hyrax
Pteropus vampyrus, large flying fox
Rattus norvegicus, Norway rat
Sarcophilus harrisii, Tasmanian devil
Sorex araneus, European shrew
Sus scrofa, pig
Tarsius syrichta, Philippine tarsier
Tupaia belangeri, northern tree shrew
Tursiops truncatus, bottlenose dolphin
Vicugna pacos, alpaca

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

pp12345pp

Tissue	Cell type	Expression level	Type	Reliability
adrenal gland	glandular tissue	Negative	Staining	Uncertain
appendix	glandular tissue	Moderate	Staining	Uncertain
appendix	lymphoid tissue	Moderate	Staining	Uncertain
bone barrow	hematopoetic stem cell	Moderate	Staining	Uncertain
breast	glandular tissue	Weak	Staining	Uncertain
bronchi	ciliated call with propulsive function of respiratory tract	Weak	Staining	Uncertain
cerebellum	granule cell	Negative	Staining	Uncertain
cerebellum		Negative	Staining	Uncertain
cerebellum	purkinje cell	Negative	Staining	Uncertain
cerebral cortex	glial cell of central nervous system	Negative	Staining	Uncertain
cerebral cortex	neuron	Negative	Staining	Uncertain
cervix of uterus	glandular tissue	Negative	Staining	Uncertain
cervix of uterus	squamous epithelial cell	Negative	Staining	Uncertain
colon	glandular tissue	Strong	Staining	Uncertain
duodenum	glandular tissue	Strong	Staining	Uncertain

pp12345pp

Classification of Transcription Factors in Mammalia

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Species specific reports

Classification of Transcription Factors in Mammalia

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Species specific reports

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