Classification of Transcription Factors in Mammalia

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1 Basic domains
- 1.1 Basic leucine zipper factors (bZIP)
- 1.2 Basic helix-loop-helix factors (bHLH)
  - 1.2.1 E2A
  - 1.2.2 MyoD-ASC-related
  - 1.2.3 Tal-related
  - 1.2.4 Hairy-related
    - 1.2.4.1 HAIRY
      - 1.2.4.1.1 HES1
      - 1.2.4.1.2 HES2
      - 1.2.4.1.3 HES3
      - 1.2.4.1.4 HES4
      - 1.2.4.1.5 HES5
      - 1.2.4.1.6 HES6
      - 1.2.4.1.7 HES7
      - 1.2.4.1.8 HEY1
      - 1.2.4.1.9 HEY2
      - 1.2.4.1.10 HEYL
      - 1.2.4.1.11 HELT
      - 1.2.4.1.12 DEC1/BHLHE40
      - 1.2.4.1.13 DEC2/BHLHE41
  - 1.2.5 PAS
  - 1.2.6 bHLH-ZIP
  - 1.2.8 HLH only
- 1.3 Basic helix-span-helix factors (bHSH)
2 Zinc-coordinating DNA-binding domains
3 Helix-turn-helix domains
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 26

Species specific reports

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Ailuropoda melanoleuca

Synonyms: giant panda

Outlinks

Ensembl gene: ENSAMEG00000009788

Bos taurus

Synonyms: cattle, domestic cow

Outlinks

Ensembl gene: ENSBTAG00000021210

Callithrix jacchus

Synonyms: white-tufted-ear marmoset, white ear-tufted marmoset

Outlinks

Ensembl gene: ENSCJAG00000000166

Canis lupus familiaris

Synonyms: dog, dogs

Outlinks

Ensembl: ENSCAFG00000019577

Cavia porcellus

Synonyms: domestic guinea pig, guinea pig

Outlinks

Ensembl: ENSCPOG00000024138

Equus caballus

Synonyms: horse, equine

Outlinks

Ensembl gene: ENSECAG00000023427

Gorilla gorilla gorilla

Synonyms: western lowland gorilla, lowland gorilla

Outlinks

Ensembl gene: ENSGGOG00000001846

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000069812
Ensembl gene: ENSG00000069812
ProteinAtlas: ENSG00000069812 ( with antibody)
TRANSFAC: T06052
UniProt: Q9Y543

Protein expression pattern:Show tableIsoforms and DNA binding domain

Ictidomys tridecemlineatus

Synonyms: thirteen-lined ground squirrel

Outlinks

Ensembl gene: ENSSTOG00000013642
UniProt: NA

Loxodonta africana

Synonyms: African savanna elephant, African savannah elephant

Outlinks

Ensembl gene: ENSLAFG00000027461
UniProt: NA

Macaca mulatta

Synonyms: Rhesus monkey, rhesus monkeys

Outlinks

Ensembl gene: ENSMMUG00000022882

Macropus eugenii

Synonyms: tammar wallaby

Outlinks

Ensembl: ENSMEUG00000001467

Microcebus murinus

Synonyms: gray mouse lemur, grey mouse lemur

Outlinks

Ensembl gene: ENSMICG00000000703
UniProt: NA

Monodelphis domestica

Synonyms: gray short-tailed opossum

Outlinks

Ensembl gene: ENSMODG00000006149
UniProt: NA

Mus musculus

Synonyms: house mouse, mouse

Outlinks

Ensembl gene: ENSMUSG00000028940
TRANSFAC: T
UniProt: O54792

Isoforms and DNA binding domain

Mustela putorius furo

Synonyms: domestic ferret, ferret

Outlinks

Ensembl: ENSMPUG00000006870

Ornithorhynchus anatinus

Synonyms: platypus, duckbill platypus

Outlinks

Ensembl gene: ENSOANG00000014690
UniProt: NA

Oryctolagus cuniculus

Synonyms: rabbit, rabbits

Outlinks

Ensembl gene: ENSOCUG00000001296

Otolemur garnettii

Synonyms: small-eared galago

Outlinks

Ensembl gene: ENSOGAG00000024214

Pan troglodytes

Synonyms: chimpanzee

Outlinks

Ensembl gene: ENSPTRG00000000085

Pongo abelii

Synonyms: Sumatran orangutan, orang utan

Outlinks

Ensembl gene: ENSPPYG00000001944

Procavia capensis

Synonyms: Cape rock hyrax, rock hyrax

Outlinks

Ensembl gene: ENSPCAG00000007135
UniProt: NA

Pteropus vampyrus

Synonyms: large flying fox

Outlinks

Ensembl gene: ENSPVAG00000013011
UniProt: NA

Rattus norvegicus

Synonyms: Norway rat, rats

Outlinks

Ensembl gene: ENSRNOG00000010490
UniProt: P35429

Isoforms and DNA binding domain

Sarcophilus harrisii

Synonyms: Tasmanian devil

Outlinks

Ensembl gene: ENSSHAG00000007537
Ensembl gene: ENSSHAG00000003355
UniProt: NA

Sus scrofa

Synonyms: pig, wild boar

Outlinks

Ensembl: ENSSSCG00000030596

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

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Tissue	Cell type	Expression level	Type	Reliability
adrenal gland	glandular tissue	Negative	Staining	Uncertain
appendix	glandular tissue	Negative	Staining	Uncertain
appendix	lymphoid tissue	Negative	Staining	Uncertain
bone barrow	hematopoetic stem cell	Weak	Staining	Uncertain
breast	glandular tissue	Negative	Staining	Uncertain
bronchi	ciliated call with propulsive function of respiratory tract	Weak	Staining	Uncertain
cerebellum	granule cell	Negative	Staining	Uncertain
cerebellum		Negative	Staining	Uncertain
cerebellum	purkinje cell	Negative	Staining	Uncertain
cerebral cortex	glial cell of central nervous system	Negative	Staining	Uncertain
cerebral cortex	neuron	Moderate	Staining	Uncertain
cervix of uterus	glandular tissue	Negative	Staining	Uncertain
cervix of uterus	squamous epithelial cell	Negative	Staining	Uncertain
colon	glandular tissue	Negative	Staining	Uncertain
duodenum	glandular tissue	Negative	Staining	Uncertain

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