Classification of Transcription Factors in Mammalia

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Family:

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1 Basic domains
- 1.1 Basic leucine zipper factors (bZIP)
  - 1.1.1 Jun-related
  - 1.1.2 Fos-related
  - 1.1.3 Maf-related
  - 1.1.4 B-ATF-related
  - 1.1.5 XBP1-related
  - 1.1.6 ATF4-related
  - 1.1.7 CREB-related
  - 1.1.8 CEBP-related
    - 1.1.8.1 CEBP
      - 1.1.8.1.1 CEBPA
      - 1.1.8.1.2 CEBPB
      - 1.1.8.1.3 CEBPG
      - 1.1.8.1.4 CEBPD
      - 1.1.8.1.5 CEBPE
      - 1.1.8.1.6 DDIT3
    - 1.1.8.2 PAR
- 1.2 Basic helix-loop-helix factors (bHLH)
- 1.3 Basic helix-span-helix factors (bHSH)
2 Zinc-coordinating DNA-binding domains
3 Helix-turn-helix domains
4 Other all-alpha-helical DNA-binding domains
5 alpha-Helices exposed by beta-structures
6 Immunoglobulin fold
7 beta-Hairpin exposed by an alpha/beta-scaffold
8 beta-Sheet binding to DNA
9 beta-Barrel DNA-binding domains
0 Yet undefined DNA-binding domains

General

Species within this Genus: 23 LOGO plot of the DNA binding sequence

Species specific reports

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Ailuropoda melanoleuca

Synonyms: giant panda

Outlinks

Ensembl gene: ENSAMEG00000013456

Callithrix jacchus

Synonyms: white-tufted-ear marmoset, white ear-tufted marmoset

Outlinks

Ensembl gene: ENSCJAG00000000526

Canis lupus familiaris

Synonyms: dog, dogs

Outlinks

Ensembl: ENSCAFG00000031326

Cavia porcellus

Synonyms: domestic guinea pig, guinea pig

Outlinks

Ensembl gene: ENSCPOG00000000811

Dasypus novemcinctus

Synonyms: nine-banded armadillo

Outlinks

Ensembl gene: ENSDNOG00000041573

Gorilla gorilla gorilla

Synonyms: western lowland gorilla, lowland gorilla

Outlinks

Ensembl gene: ENSGGOG00000025010

Homo sapiens

Synonyms: human, man

Outlinks

BioGPS: ENSG00000172216
Ensembl gene: ENSG00000172216
ProteinAtlas: ENSG00000172216 ( with antibody)
TRANSFAC: T00581
UniProt: P17676

Protein expression pattern:Show tableIsoforms and DNA binding domain

Loxodonta africana

Synonyms: African savanna elephant, African savannah elephant

Outlinks

Ensembl gene: ENSLAFG00000026180
UniProt: NA

Macaca mulatta

Synonyms: Rhesus monkey, rhesus monkeys

Outlinks

Ensembl: ENSMMUG00000004874

Macropus eugenii

Synonyms: tammar wallaby

Outlinks

Ensembl: ENSMEUG00000000063

Monodelphis domestica

Synonyms: gray short-tailed opossum

Outlinks

Ensembl gene: ENSMODG00000016314
UniProt: NA

Mus musculus

Synonyms: house mouse, mouse

Outlinks

Ensembl gene: ENSMUSG00000056501
TRANSFAC: T09409
UniProt: P28033

Isoforms and DNA binding domain

Mustela putorius furo

Synonyms: domestic ferret, ferret

Outlinks

Ensembl: ENSMPUG00000019019

Myotis lucifugus

Synonyms: little brown bat

Outlinks

Ensembl gene: ENSMLUG00000002060
UniProt: NA

Oryctolagus cuniculus

Synonyms: rabbit, rabbits

Outlinks

Ensembl gene: ENSOCUG00000024667

Otolemur garnettii

Synonyms: small-eared galago

Outlinks

Ensembl gene: ENSOGAG00000026467

Ovis aries

Synonyms: sheep, wild sheep

Outlinks

Ensembl gene: ENSOARG00000013395

Pan troglodytes

Synonyms: chimpanzee

Outlinks

Ensembl gene: ENSPTRG00000041263

Pongo abelii

Synonyms: Sumatran orangutan, orang utan

Outlinks

Ensembl gene: ENSPPYG00000011124

Pteropus vampyrus

Synonyms: large flying fox

Outlinks

Ensembl gene: ENSPVAG00000003541
UniProt: NA

Rattus norvegicus

Synonyms: Norway rat, rats

Outlinks

Ensembl: ENSRNOG00000049393

Sus scrofa

Synonyms: pig, wild boar

Outlinks

Ensembl: ENSSSCG00000028739
Ensembl: ENSSSCG00000024816

Tursiops truncatus

Synonyms: bottlenose dolphin, bottle-nosed dolphin

Outlinks

Ensembl gene: ENSTTRG00000003985
UniProt: NA

Expression table

The table below summarizes the protein expression data from the Protein Atlas. The tissues and cell types are linked to the Cytomer ontology

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Tissue	Cell type	Expression level	Type	Reliability
adrenal gland	glandular tissue	Strong	Staining	Supportive
appendix	glandular tissue	Moderate	Staining	Supportive
appendix	lymphoid tissue	Weak	Staining	Supportive
bone barrow	hematopoetic stem cell	Strong	Staining	Supportive
breast	glandular tissue	Strong	Staining	Supportive
bronchi	ciliated call with propulsive function of respiratory tract	Strong	Staining	Supportive
cerebellum	granule cell	Moderate	Staining	Supportive
cerebellum		Moderate	Staining	Supportive
cerebellum	purkinje cell	Negative	Staining	Supportive
cerebral cortex	glial cell of central nervous system	Moderate	Staining	Supportive
cerebral cortex	neuron	Negative	Staining	Supportive
cervix of uterus	glandular tissue	Strong	Staining	Supportive
cervix of uterus	squamous epithelial cell	Strong	Staining	Supportive
colon	glandular tissue	Moderate	Staining	Supportive
duodenum	glandular tissue	Moderate	Staining	Supportive

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